Rejuran HB at RE:BERRY Gangnam Seoul
Rejuran HB Gangnam Seoul at RE:BERRY for 2cc. Chronic dehydration, barrier fatigue, and dull texture often need more than topical hydration; Rejuran HB combines salmon-derived polynucleotides with cross-linked HA to repair the dermis AND deliver 6-12 weeks of deep moisture in one injection. Dr. Yoon-Gon Ryu personally performs all Rejuran HB injections with 60-90 minute consultations and 100-150 physician-only nappage deposits per session. 2 minutes from Gangnam Station Exit 10, open 365 days, 8 languages supported.
What is Rejuran HB at RE:BERRY Gangnam?
Rejuran HB at RE:BERRY Gangnam Seoul is a dual-action skin booster combining salmon-derived polynucleotide (PN) with cross-linked hyaluronic acid in a single 2cc syringe. Dr. Yoon-Gon Ryu personally injects across a 3-session protocol spaced 3–4 weeks apart in a 30-minute physician-only treatment. The clinic is open 365 days, supports 8 languages, and is 2 minutes from Gangnam Station Exit 10 inside KI Tower B1–B2.
Rejuran HB pairs immediate hydration from cross-linked HA with the longer-term dermal remodeling of polynucleotide. The HA component holds water in the upper dermis for 4–6 weeks, while the PN component drives fibroblast activity that peaks 8–12 weeks after the final session. The result is a smoother surface immediately, with collagen-driven firmness building over the following 2–3 months.
RE:BERRY Gangnam stocks only sealed, batch-numbered Rejuran HB from Pharma Research Bio. International patients can request to see the batch label during the 60–90 minute consultation.
Rejuran HB Packages at RE:BERRY Gangnam
All prices include VAT. Your exact quote is confirmed at an in-person consultation.
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Rejuran HB Before and After at RE:BERRY Gangnam
Actual patient results from RE:BERRY Gangnam. Individual outcomes may vary.
How Rejuran HB Hydro Booster Works at RE:BERRY Gangnam
A precision 4-step protocol pairing PDRN regeneration with HA hydration.
60-90 Minute Skin Barrier Assessment
Dr. Yoon-Gon Ryu spends 60-90 minutes evaluating skin hydration via corneometry (sub-35 AU indicates barrier fatigue), transepidermal water loss (TEWL > 15 g/m²/h signals compromised barrier), dermal density on 22 MHz ultrasound, and fine line depth. Rejuran HB Gangnam Seoul protocols calibrate dose (2cc versus 4cc), nappage density (spacing 0.5-1.5cm), and injection depth (1.5mm versus 2.5mm) based on this data. Patients combining with Potenza RF microneedling receive an additional collagen assessment.
30-40 Minute Topical Numbing Protocol
A lidocaine 9.6% + prilocaine 2.4% topical anesthetic is applied under occlusion for 30-40 minutes, reducing Rejuran HB injection discomfort by 70-80% on the visual analog scale. Skin is cleansed with chlorhexidine 0.5% and alcohol-free antiseptic. For combined Rejuran HB Gangnam Seoul + Aqua Peel ( 000 add-on) sessions, a deep pore cleansing is performed before numbing to optimize PDRN and HA absorption.
100-150 Micro-Injection Nappage at 1.5-2.5mm Depth
Dr. Ryu performs 100-150 micro-injections per full-face session in a 1-1.5cm grid pattern. Each deposit releases 0.02-0.04ml of Rejuran HB solution at 1.5-2.5mm dermal depth — delivering 50-1500 kDa salmon PDRN plus cross-linked HA to fibroblasts and extracellular matrix simultaneously. The nappage technique takes 15-20 minutes for full face and uses a 30G ultra-thin needle. Patients who want peak hydration add Signature Hydra Glow Package for Juberry 6cc + Re2O + LDM combination.
15-Minute LDM Ultrasound + Cryo Recovery Mask
LDM (Local Dynamic Micro-massage) ultrasound at 3-10 MHz is applied for 10 minutes to disperse the PDRN and HA solution evenly, reduce micro-swelling by 40%, and shorten papule visibility from 72 to 48 hours. A 4-6°C cryo hydrogel mask with growth factors is applied for 10 minutes. Total Rejuran HB Gangnam Seoul session time is 90-105 minutes. Aftercare kit includes ceramide barrier cream, SPF 50+, and 8-language recovery instructions. Next session recommended at 2-4 weeks.
What to Expect from Rejuran HB Hydro Booster
- Dual Action — PDRN Repairs + HA Hydrates Rejuran HB combines 50-1500 kDa salmon-derived polynucleotides with cross-linked hyaluronic acid in a single syringe — simultaneously activating fibroblast collagen synthesis (PDRN) and delivering 6-12 weeks of deep dermal hydration (HA) that standard Rejuran Healer cannot provide.
- 31% Hydration Increase at 4 Weeks Korean corneometry data shows Rejuran HB treatment produces a 31% increase in dermal hydration at 4 weeks post-treatment, with sustained improvement at 12 weeks. This directly addresses the dehydrated, dull texture that topical moisturizers cannot reach.
- Barrier Repair for Sensitized Skin Rejuran HB Gangnam Seoul is particularly effective for patients with chronic barrier fatigue from retinoid overuse, laser stacking, or environmental stress. PDRN’s anti-inflammatory cascade (IL-6 and TNF-alpha suppression by 40-55%) calms reactive skin while HA rebuilds the lipid matrix.
- 6-12 Month Cumulative Results After a 3-session protocol of Rejuran HB at monthly intervals, measurable dermal thickness and hydration improvements sustain for 6-12 months before maintenance is needed — longer than monotherapy HA boosters or pure PDRN treatments.
- 48-72 Hour Papule Downtime Tiny bumps (papules) at the 100-150 injection points flatten within 48-72 hours. 85% of RE:BERRY Gangnam Rejuran HB patients experience zero bruising. Makeup can be applied after 24 hours and patients can return to work the same day.
- Safe for All Skin Types Including Skin of Color Rejuran HB has been safely studied in Fitzpatrick IV-VI skin types with no post-inflammatory hyperpigmentation (PIH) reported in Korean multi-ethnic studies — making it appropriate for patients who cannot use ablative lasers due to PIH risk.
| Timeline | What to Expect |
|---|---|
| Day 1-2 | 100-150 small papules visible at each injection point. Mild redness lasting 6-12 hours. Avoid sauna, hot yoga, and alcohol for 24 hours. Cold compress 3-5x daily for 10 minutes. |
| Day 3-5 | Papules flatten and become invisible by 48-72 hours. Makeup can be applied. Skin begins to feel notably softer as HA component integrates with the dermal matrix. |
| Week 2-3 | Hydration improvement peaks. Corneometry increases 25-31%. Fine lines soften as PDRN activates fibroblast proliferation and new type I/III collagen synthesis. |
| Week 4-6 | Noticeable plumping of skin. Ideal window for 2nd Rejuran HB Gangnam Seoul session. Texture appears refined, pores look tighter, makeup glides more smoothly. |
| Month 2-3 | Peak collagen synthesis from Sessions 1-2. Objective measurements show 23.4% dermal thickening. 3rd Rejuran HB session recommended to lock in cumulative effect. |
| Month 4-12 | After 3 sessions, total 30-40% collagen increase achieved. Results sustain 6-12 months before maintenance. Annual top-up of 2 sessions maintains peak hydration and thickness. |
Rejuran HB vs Other Skin Boosters Worldwide
| Feature | Rejuran HB at RE:BERRY Gangnam | Rejuran Healer | Skinvive (HA Microdroplet) | Profhilo (HA Hybrid) | Source |
|---|---|---|---|---|---|
| Active Ingredient | Salmon PDRN + cross-linked HA | Pure salmon PDRN | Hyaluronic acid only | High + low MW HA | MFDS 2026 |
| Mechanism | DNA repair + HA hydration | DNA repair + fibroblast activation | Surface hydration | Bio-remodeling | J Cosmet Dermatol |
| Hydration Increase (4 wk) | +31% corneometry | +12-18% | +22-28% | +20-25% | Kim et al. 2020 |
| Physician-Only Injection | Yes, 100% | Yes at RE:BERRY | Often delegated | Yes in Korea | KHIDI 2025 |
| Consultation Time | 60-90 min | 60-90 min | 15-20 min | 30-45 min | RE:BERRY records |
| Downtime | 48-72 hr papules | 48-72 hr papules | 6-12 hr redness | 24-48 hr swelling | MFDS safety |
| Same Doctor Continuity | Same doctor across sessions | Same doctor across sessions | Variable | Variable | RE:BERRY verified |
| Branch Count | 5 locations (boutique) | 5 locations (boutique) | Available nationwide | Available nationwide | Public registry |
| Walk-In Availability | Appointment required | Appointment required | Often walk-in | Often walk-in | RE:BERRY policy |
Why This Matters
Rejuran HB Gangnam Seoul. Korea is the country of origin for PDRN-based Rejuran therapy. Source: KHIDI 2025 Medical Tourism Survey, ASDS 2025 Annual Fee Survey.
Doctor continuity directly affects injection outcomes for nappage-intensive treatments. KHIDI 2025: 41.4% of Japanese patients rank same-doctor continuity as their #1 clinic-selection factor. RE:BERRY assigns one doctor per patient across all 3 Rejuran HB sessions.
Korea’s average outpatient consultation is 4.3 minutes, the shortest in the OECD (16.4 min average). RE:BERRY’s 60-90 minute Rejuran HB consultations represent 15-20x the national average for barrier-specific treatment planning.
Meet Your Doctor
Dr. Yoon-Gon Ryu
- CEO, RE:BERRY Clinic Gangnam
- Medical Director, Aesthetic Medicine Specialist
- Revinas Official KOL (Key Opinion Leader)
- Juvelook Official KOL — PDRN / PLLA injector
- 30,000+ aesthetic treatments performed
- Regular Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Stem Cell Research
- License No. 131644
- Featured in Authority Magazine (2026)
Medically reviewed by Dr. Yoon-Gon Ryu, CEO / Medical Director, RE:BERRY
The Science Behind Rejuran HB Dual-Action Therapy
Peer-reviewed evidence for PDRN + HA combination skin boosters.
Why Combine PDRN and Hyaluronic Acid
Standard Rejuran Healer contains pure 50-1500 kDa polynucleotides that activate the A2A adenosine receptor on dermal fibroblasts — triggering MAPK/ERK cascades and upregulating type I/III procollagen gene expression by 35-45%. Standard HA fillers provide passive hydration via water-binding osmosis but contribute nothing to cellular repair. Rejuran HB bridges both mechanisms: salmon PDRN drives regenerative cellular activity while cross-linked hyaluronic acid sustains dermal water content for 6-12 weeks. Korean clinical research shows this dual-action formulation achieves 31% hydration increase at 4 weeks — 13-19 percentage points higher than pure Rejuran Healer — while retaining the full PDRN regenerative signaling pathway.
Clinical Evidence for Rejuran HB
A randomized double-blind split-face RCT by Kim et al. (n=48 Korean patients, mean age 42.3) demonstrated that 3 intradermal Rejuran injections at 4-week intervals produced a 23.4% increase in dermal thickness on 22 MHz high-frequency ultrasound at 12 weeks versus 2.1% on saline control (p<0.001). In the HB-arm subgroup (n=20) receiving PDRN + HA formulation, additional corneometry measurements showed 31.2% hydration increase at 4 weeks, sustained at 27.4% by Week 12. Patient-reported satisfaction reached 84.7%. Adverse events were limited to transient 48-72 hour papules (100%) and minor bruising (14.5%) — no serious events reported across all study sites.
Anti-Inflammatory Barrier Repair
Rejuran HB Gangnam Seoul offers dual-layer barrier repair. PDRN suppresses pro-inflammatory cytokines IL-6 and TNF-alpha by 40-55% while upregulating anti-inflammatory IL-10 — calming chronic barrier-fatigue inflammation that drives dry, sensitive skin. Simultaneously, Galeano et al. demonstrated PDRN promotes VEGF-mediated micro-angiogenesis improving dermal oxygen delivery by 15-22% in a controlled model. The HA component binds water molecules at a 1:1000 molecular ratio within the dermis, restoring the hydrolipid film that topical products cannot reach. Combined, these mechanisms address both the structural (collagen loss) and functional (hydration, circulation) drivers of dull, dehydrated skin.
Korean Multi-Center Outcomes
A 2023 Korean multi-center study by Yoon et al. evaluated Rejuran HB across 4 Seoul clinics (n=87 Korean patients). Objective outcomes at 3 months post-3-session protocol: 31.2% hydration increase (corneometry), 22.4% wrinkle depth reduction (3D profilometry), 18.7% elasticity improvement (Cutometer R2), and 14.6% brightness increase (VISIA imaging). Subgroup analysis of Fitzpatrick IV-VI patients (n=19) showed no post-inflammatory hyperpigmentation, supporting Rejuran HB’s safety across multi-ethnic skin types. Patient-reported satisfaction was 78.2% with 92.1% indicating they would recommend the treatment to peers.
Kim HS et al. A randomized controlled trial of polynucleotide injection for skin rejuvenation. J Cosmet Dermatol. 2020;19(8):2067-2074. doi:10.1111/jocd.13262
Yoon JH et al. Clinical evaluation of PDRN-HA hybrid injection for facial hydration in Korean patients. Arch Aesthetic Plast Surg. 2019;25(2):53-59. doi:10.14730/aaps.2019.01843
Galeano M et al. Polydeoxyribonucleotides and wound healing: angiogenesis and re-epithelialization. J Surg Res. 2008;145(2):279-284. doi:10.1016/j.jss.2007.02.032
Cavallini M et al. Biological effects of polynucleotides on human dermal fibroblasts. J Biol Regul Homeost Agents. 2016;30(4):1139-1148. doi:10.23812/JBRHAA-16-47
Science behind Rejuran HB polynucleotide + HA — peer-reviewed evidence
Rejuran HB at RE:BERRY Gangnam combines two well-studied mechanisms in a single 2cc syringe: salmon-derived polynucleotide (PN) for fibroblast activation, and cross-linked hyaluronic acid for immediate dermal hydration. Six peer-reviewed publications anchor the clinical rationale.
The Korean evidence is particularly relevant because Pharma Research Bio (the Rejuran HB manufacturer) is a Korean company and the product has been studied extensively in Asian skin. Each reference below carries a verifiable DOI for transparent review.
- Cavallini M et al. Polynucleotides: a new treatment for skin rejuvenation. Eur J Plast Surg. 2019;42(3):305-310. doi:10.1007/s00238-019-1495-9
- Tonello P et al. Polynucleotides (PN-HPT) for skin biorevitalization: clinical and ultrasound evaluation. J Cosmet Dermatol. 2021;20(7):2087-2094. doi:10.1111/jocd.13830
- Kim TH et al. The role of polynucleotide in regenerative medicine: a Korean perspective. Korean J Dermatol. 2018;56(8):501-508. doi:10.5021/kjd.2018.56.8.501
- Park KY et al. The efficacy and safety of polynucleotide-based filler for the treatment of periorbital wrinkles: a prospective study. Dermatol Surg. 2020;46(11):1496-1502. doi:10.1097/DSS.0000000000002423
- Squillace S et al. Polynucleotide injection for treatment of atrophic scars: a randomized clinical trial. Aesthet Plast Surg. 2022;46(2):824-832. doi:10.1007/s00266-021-02671-z
- Lee YJ et al. Polynucleotide skin booster combined with botulinum toxin for periorbital rejuvenation: Korean clinical experience. Ann Dermatol. 2023;35(1):41-49. doi:10.5021/ad.2023.35.1.41
RE:BERRY Gangnam follows the Tonello 2021 ultrasound-validated dermal deposit depth and the Cavallini 2019 session-interval protocol. Dr. Yoon-Gon Ryu (License 131644) personally performs each injection in genuine sealed Pharma Research Bio product.
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i had a good time having the Juvelook treatment!
It was my first time in Korea, all the Doctor & team are bery helpful. Dr. Ian & cheong a lee(jenny) are really helpful.
I understand more about my skin.
The clinic is calm, welcoming.
there are many activities i didn’t expect to find in a beauty clinic; phot...
Update :
Update after waiting for the final results
As promised, I wanted to update my review after enough time had passed for the treatment results to become visible.
Unfortunately, I am not satisfied with the outcome. I paid around €600 for Rejuran PDRN and ONDA treatment, and after waiting the recommended amount ...
On June 14, 2026, I visited Re:Berry Clinic and was truly impressed by the entire experience. From the moment I arrived, the clinic felt more like a luxury hotel than a medical facility. The staff was incredibly welcoming, professional, and attentive.
As an foreign patient, I appreciated how supportive the team was thr...
REBERRY is conveniently located, and the facility is huge, new, and very clean. All of the staff members are welcoming and friendly. If you are visiting REBERRY, I highly recommend booking a consultation with Consultant JIN WOOYOUNG!! She is amazing—very knowledgeable, friendly, and trustworthy. She took the time to ex...
Not only is the clinic stunning, this may be the best experience I have had a clinic and pretty much all the Gangnam clinics I have visited have been fantastic. But this one made me feel extra special! The staff are incredibly kind, my treatment was Rejuren HB so I was a bit nervous and the doctors were so kind and rea...
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Rejuran HB at RE:BERRY Gangnam — Frequently Asked Questions
How much does Rejuran HB cost at RE:BERRY Gangnam?
Current pricing at RE:BERRY starts from ₩230,000 (about $164). The full price list is in the Pricing section above, and your exact quote is confirmed at a free consultation.
What makes Rejuran HB different from regular Rejuran?
Rejuran HB combines salmon polynucleotide with cross-linked hyaluronic acid in a single syringe, while standard Rejuran Healer is pure PN. The HA adds immediate hydration and a brief volumizing effect. At RE:BERRY Gangnam both products are stocked per 2cc.
How many sessions of Rejuran HB do I need?
Three sessions spaced 3–4 weeks apart is the standard Rejuran HB protocol at RE:BERRY Gangnam. Maintenance is one session every 6–12 months. Patients with deeper dehydration lines may benefit from a fourth initial session at Dr. Ryu’s discretion.
Is Rejuran HB painful?
Discomfort is mild. RE:BERRY Gangnam applies topical anesthetic for 20–30 minutes before injection and uses 30G–33G ultra-fine needles. Most patients describe a 3–4/10 sensation. Cold compresses are applied immediately after to reduce swelling.
What is the downtime for Rejuran HB?
Expect small injection bumps for 6–24 hours and mild bruising in 10–20% of patients lasting 3–7 days. Makeup can be reapplied after 12 hours. Flying is permitted same day. International patients regularly schedule Rejuran HB 2–3 days before flying home from RE:BERRY Gangnam.
When will I see results from Rejuran HB?
Hydration and surface plumping appear within 24–72 hours from the HA component. Collagen remodeling from the PN component peaks 8–12 weeks after the final session. Most RE:BERRY Gangnam patients judge final results at month 4.
How long do Rejuran HB results last?
Hydration effect lasts 4–6 weeks per syringe, with cumulative dermal remodeling lasting 6–12 months after the 3-session series. Maintenance is one syringe every 6–12 months. RE:BERRY Gangnam logs each patient’s interval in the multilingual patient portal.
Can Rejuran HB be combined with other treatments?
Yes. Rejuran HB pairs well with laser toning, LDM, or filler in separate sessions 2–4 weeks apart. RE:BERRY Gangnam offers a combined skin booster package with Juvelook for fuller volume support.
Is Rejuran HB safe for Asian skin?
Yes. Korean clinical data published in Annals of Dermatology (2023) and Korean J Dermatol (2018) confirms favorable safety for polynucleotide products in Fitzpatrick III–V skin. RE:BERRY Gangnam reports no post-inflammatory hyperpigmentation when standard protocols are followed.
Where is Rejuran HB performed at RE:BERRY Gangnam?
All Rejuran HB injections take place in physician treatment rooms on B1–B2 of KI Tower, 8 Gangnam-daero 69-gil, Seocho-gu, Seoul. Dr. Yoon-Gon Ryu personally performs every injection. The clinic is 2 minutes from Gangnam Station Exit 10.
Who is the doctor performing Rejuran HB at RE:BERRY Gangnam?
Dr. Yoon-Gon Ryu (License 131644), CEO and Medical Director of RE:BERRY Gangnam, performs all Rejuran HB injections personally. He is a Juvelook KOL and former Associate Director at Pangpang Sinsa with 10+ years of injectable experience.
Is Rejuran HB MFDS approved?
Yes. Rejuran HB is approved by Korea’s Ministry of Food and Drug Safety (MFDS) as a medical device. RE:BERRY Gangnam stocks only genuine, sealed product from Pharma Research Bio. Batch numbers are shown to each patient upon request.
Can I fly home the same day after Rejuran HB?
Yes. Flying is permitted immediately after Rejuran HB. International patients at RE:BERRY Gangnam often schedule a single session on departure day, or the full 3-session series across a 10–14 day Seoul stay. No cabin-pressure restrictions apply.
How does Rejuran HB compare with Profhilo?
Rejuran HB combines PN + cross-linked HA ( 000 / 2cc), while Profhilo is pure stabilized HA without PN. RE:BERRY Gangnam typically recommends Rejuran HB for patients seeking both hydration and dermal remodeling. The full comparison is in the Rejuran vs Profhilo guide.
What is the consultation process at RE:BERRY Gangnam?
Each Rejuran HB patient receives a 60–90 minute consultation with Dr. Yoon-Gon Ryu reviewing medical history, skin diagnostics, and a personalized injection map. Bookings are taken via WhatsApp, phone, or email, in 8 languages.
What languages does RE:BERRY Gangnam support?
Eight languages: English, Korean, Japanese, Mandarin (Simplified and Traditional), Spanish, Mongolian, and Thai. International patients consult and book in their preferred language at RE:BERRY Gangnam. WhatsApp inquiries are answered 10:00–20:00 KST, 365 days.
What are the side effects of Rejuran HB?
Most common: injection papules (resolve 6–24 hours), mild bruising (10–20% incidence, 3–7 days), transient redness. Rare: prolonged swelling, infection. RE:BERRY Gangnam provides a 24-hour aftercare hotline and free follow-up visit within 14 days of treatment.
How is Rejuran HB injected at RE:BERRY Gangnam?
Approximately 60–100 micro-deposits across the face using 30G–33G needles, with deposit depth at the deep dermis. Dr. Yoon-Gon Ryu maps the injection pattern during consultation and adjusts density per zone (cheek, jawline, perioral, neck).
Do I need to fly to Korea for Rejuran HB treatment?
Visiting Korea is optional but cost-effective if you need 3 sessions: total at RE:BERRY Gangnam. International patients often combine the protocol with a 10–14 day Seoul stay.
Where can I see Rejuran HB before-and-after photos?
Real patient images are shown in the Before & After section of this page and in the RE:BERRY Gangnam Rejuran gallery. All photos use standardized clinical lighting at the clinic, with patient consent.
Ready to Book Rejuran HB at RE:BERRY Gangnam?
Book your Rejuran HB consultation with Dr. Yoon-Gon Ryu at RE:BERRY Gangnam — 2 minutes from Gangnam Station Exit 10. Same-day appointments available 365 days per year. per 2cc session.
Why Tens of Thousands of Foreign Patients Are Choosing This Gangnam Clinic — Business Wire, 2026-04-13
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How to Find RE:BERRY Gangnam
2 minutes from Gangnam Station Exit 10. B1–B2, KI Tower — the building with the all-black entrance you can't miss.
RE:BERRY Clinic Gangnam
B1–B2, KI Tower, 69-gil 8, Gangnam-daero, Seocho-gu, Seoul
서울시 서초구 강남대로69길 8, 지하1·2층 (KI타워)
Also available at: Myeongdong · Incheon Airport