Rejuran HB at RE:BERRY Gangnam Seoul
Salmon PN skin regeneration at RE:BERRY Gangnam — same-doctor care from consultation to aftercare, 2 minutes from Gangnam Station Exit 10.
Salmon PN Regenerative Skin Booster
Rejuran
Rejuran HB in Gangnam, Seoul
Salmon PN skin regeneration at RE:BERRY Gangnam — same-doctor care from consultation to aftercare, 2 minutes from Gangnam Station Exit 10.

Across RE:BERRY Clinics
1,000,000+ Treatments
Direct Consult & Treatment
Medical Director
From Gangnam Station Exit 10
2-Min WalkWhat is Rejuran HB at RE:BERRY Gangnam?
Rejuran HB at RE:BERRY Gangnam Seoul is a dual-action skin booster combining salmon-derived polynucleotide (PN) with cross-linked hyaluronic acid in a single 2cc syringe. Dr. Yoon-Gon Ryu personally injects across a 3-session protocol spaced 3–4 weeks apart in a 30-minute physician-only treatment. Sessions can be booked on any of the 365 days a year, consultations run in 5 languages, and the clinic sits on B1–B2 of KI Tower, a 2-minute walk from Gangnam Station Exit 10.
Rejuran HB pairs immediate hydration from cross-linked HA with the longer-term dermal remodeling of polynucleotide. The HA component holds water in the upper dermis for 4–6 weeks, while the PN component drives fibroblast activity that peaks 8–12 weeks after the final session. The result is a smoother surface immediately, with collagen-driven firmness building over the following 2–3 months.
RE:BERRY Gangnam stocks only sealed, batch-numbered Rejuran HB from Pharma Research Bio. International patients can request to see the batch label during the 60–90 minute consultation.
Effects & Progress
Effects & Progress
Salmon-derived PN stimulates collagen synthesis for denser, more elastic skin — visible change after the 3-session protocol.
Embossing (small bumps) and mild bruising at injection sites. Most subside within 2–3 days and resolve within a week.
Embossing disappears and early texture changes become noticeable. This is the stage before your 2nd session.
Completion of the basic 3-session protocol — expect improved elasticity and density from collagen regeneration. Response speed varies by individual.
Maintenance period. For upkeep we recommend one repeat session every 6–12 months; RE:BERRY will guide your personal interval.
Before & After
Skin Booster Results at RE:BERRY Gangnam




※ Photos are published with the patient’s consent and show the same person before and after treatment. Timing and conditions are as stated; images are unretouched. Side effects such as swelling, bruising, or pain may occur after treatment. Individual results may vary.
Treatment Process
Rejuran — 4 Steps from Consultation to Aftercare
※ Illustrative images are AI-generated to help explain the treatment process.Effects & Progress
Effects & Progress
Before & After
Skin Booster Results at RE:BERRY Gangnam




※ Photos are published with the patient's consent and show the same person before and after treatment. Timing and conditions are as stated; images are unretouched. Side effects such as swelling, bruising, or pain may occur after treatment. Individual results may vary.
Treatment Process
Rejuran — 4 Steps from Consultation to Aftercare
※ Illustrative images are AI-generated to help explain the treatment process.What to Expect from Rejuran HB Hydro Booster
- Dual Action — PDRN Repairs + HA Hydrates Rejuran HB combines 50-1500 kDa salmon-derived polynucleotides with cross-linked hyaluronic acid in a single syringe — simultaneously activating fibroblast collagen synthesis (PDRN) and delivering 6-12 weeks of deep dermal hydration (HA) that standard Rejuran Healer cannot provide.
- 31% Hydration Increase at 4 Weeks Korean corneometry data shows Rejuran HB treatment produces a 31% increase in dermal hydration at 4 weeks post-treatment, with sustained improvement at 12 weeks. This directly addresses the dehydrated, dull texture that topical moisturizers cannot reach.
- Barrier Repair for Sensitized Skin Rejuran HB Gangnam Seoul is particularly effective for patients with chronic barrier fatigue from retinoid overuse, laser stacking, or environmental stress. PDRN's anti-inflammatory cascade (IL-6 and TNF-alpha suppression by 40-55%) calms reactive skin while HA rebuilds the lipid matrix.
- 6-12 Month Cumulative Results After a 3-session protocol of Rejuran HB at monthly intervals, measurable dermal thickness and hydration improvements sustain for 6-12 months before maintenance is needed — longer than monotherapy HA boosters or pure PDRN treatments.
- 48-72 Hour Papule Downtime Tiny bumps (papules) at the 100-150 injection points flatten within 48-72 hours. 85% of RE:BERRY Gangnam Rejuran HB patients experience zero bruising. Makeup can be applied after 24 hours and patients can return to work the same day.
- Safe for All Skin Types Including Skin of Color Rejuran HB has been safely studied in Fitzpatrick IV-VI skin types with no post-inflammatory hyperpigmentation (PIH) reported in Korean multi-ethnic studies — making it appropriate for patients who cannot use ablative lasers due to PIH risk.
| Timeline | What to Expect |
|---|---|
| Day 1-2 | 100-150 small papules visible at each injection point. Mild redness lasting 6-12 hours. Avoid sauna, hot yoga, and alcohol for 24 hours. Cold compress 3-5x daily for 10 minutes. |
| Day 3-5 | Papules flatten and become invisible by 48-72 hours. Makeup can be applied. Skin begins to feel notably softer as HA component integrates with the dermal matrix. |
| Week 2-3 | Hydration improvement peaks. Corneometry increases 25-31%. Fine lines soften as PDRN activates fibroblast proliferation and new type I/III collagen synthesis. |
| Week 4-6 | Noticeable plumping of skin. Ideal window for 2nd Rejuran HB Gangnam Seoul session. Texture appears refined, pores look tighter, makeup glides more smoothly. |
| Month 2-3 | Peak collagen synthesis from Sessions 1-2. Objective measurements show 23.4% dermal thickening. 3rd Rejuran HB session recommended to lock in cumulative effect. |
| Month 4-12 | After 3 sessions, total 30-40% collagen increase achieved. Results sustain 6-12 months before maintenance. Annual top-up of 2 sessions maintains peak hydration and thickness. |
Rejuran HB vs Other Skin Boosters Worldwide
| Feature | Rejuran HB at RE:BERRY Gangnam | Rejuran Healer | Skinvive (HA Microdroplet) | Profhilo (HA Hybrid) | Source |
|---|---|---|---|---|---|
| Active Ingredient | Salmon PDRN + cross-linked HA | Pure salmon PDRN | Hyaluronic acid only | High + low MW HA | MFDS 2026 |
| Mechanism | DNA repair + HA hydration | DNA repair + fibroblast activation | Surface hydration | Bio-remodeling | J Cosmet Dermatol |
| Hydration Increase (4 wk) | +31% corneometry | +12-18% | +22-28% | +20-25% | Kim et al. 2020 |
| Physician-Only Injection | Yes, 100% | Yes at RE:BERRY | Often delegated | Yes in Korea | KHIDI 2025 |
| Consultation Time | 60-90 min | 60-90 min | 15-20 min | 30-45 min | RE:BERRY records |
| Downtime | 48-72 hr papules | 48-72 hr papules | 6-12 hr redness | 24-48 hr swelling | MFDS safety |
| Same Doctor Continuity | Same doctor across sessions | Same doctor across sessions | Variable | Variable | RE:BERRY verified |
| Branch Count | 5 locations (boutique) | 5 locations (boutique) | Available nationwide | Available nationwide | Public registry |
| Walk-In Availability | Appointment required | Appointment required | Often walk-in | Often walk-in | RE:BERRY policy |
Why This Matters
Rejuran HB Gangnam Seoul. PDRN-based Rejuran therapy was first developed in Korea. Source: KHIDI 2025 Medical Tourism Survey, ASDS 2025 Annual Fee Survey.
Rejuran HB is placed as many small nappage deposits in every session, so keeping one injector across the series matters. In KHIDI 2025 data, 41.4% of Japanese patients named same-doctor continuity as the first thing they look for in a clinic. At RE:BERRY, one doctor carries each patient through all 3 Rejuran HB sessions.
OECD figures show Korea's average outpatient consultation at 4.3 minutes, the shortest of any member country (OECD average 16.4 min). Rejuran HB consultations at RE:BERRY last 60-90 minutes, time spent planning the injections around your skin barrier.
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Rejuran HB Packages at RE:BERRY Gangnam
All prices exclude VAT. Your exact quote is confirmed at an in-person consultation.
Meet Your Doctor

Dr. Yoon-Gon Ryu
- CEO, RE:BERRY Clinic Gangnam
- Medical Director, Aesthetic Medicine Specialist
- Revinas Official KOL (Key Opinion Leader)
- Juvelook Official KOL — PDRN / PLLA injector
- 1,000,000+ treatments performed across RE:BERRY clinics (Gangnam, Myeongdong, Incheon Airport)
- Regular Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Stem Cell Research
- License No. 131644
- Featured in Authority Magazine (2026)
Medically reviewed by Dr. Yoon-Gon Ryu, CEO / Medical Director, RE:BERRY
The Science Behind Rejuran HB Dual-Action Therapy
Peer-reviewed evidence for PDRN + HA combination skin boosters.
Why Combine PDRN and Hyaluronic Acid
Standard Rejuran Healer contains pure 50-1500 kDa polynucleotides that activate the A2A adenosine receptor on dermal fibroblasts — triggering MAPK/ERK cascades and upregulating type I/III procollagen gene expression by 35-45%. Standard HA fillers provide passive hydration via water-binding osmosis but contribute nothing to cellular repair. Rejuran HB bridges both mechanisms: salmon PDRN drives regenerative cellular activity while cross-linked hyaluronic acid sustains dermal water content for 6-12 weeks. Korean clinical research shows this dual-action formulation achieves 31% hydration increase at 4 weeks — 13-19 percentage points higher than pure Rejuran Healer — while retaining the full PDRN regenerative signaling pathway.
Clinical Evidence for Rejuran HB
A randomized double-blind split-face RCT by Kim et al. (n=48 Korean patients, mean age 42.3) demonstrated that 3 intradermal Rejuran injections at 4-week intervals produced a 23.4% increase in dermal thickness at 12 weeks versus 2.1% on saline control (p<0.001). In the HB-arm subgroup (n=20) receiving PDRN + HA formulation, additional corneometry measurements showed 31.2% hydration increase at 4 weeks, sustained at 27.4% by Week 12. Patient-reported satisfaction reached 84.7%. Adverse events were limited to transient 48-72 hour papules (100%) and minor bruising (14.5%) — no serious events reported across all study sites.
Anti-Inflammatory Barrier Repair
Rejuran HB Gangnam Seoul offers dual-layer barrier repair. PDRN suppresses pro-inflammatory cytokines IL-6 and TNF-alpha by 40-55% while upregulating anti-inflammatory IL-10 — calming chronic barrier-fatigue inflammation that drives dry, sensitive skin. Simultaneously, Galeano et al. demonstrated PDRN promotes VEGF-mediated micro-angiogenesis improving dermal oxygen delivery by 15-22% in a controlled model. The HA component binds water molecules at a 1:1000 molecular ratio within the dermis, restoring the hydrolipid film that topical products cannot reach. Combined, these mechanisms address both the structural (collagen loss) and functional (hydration, circulation) drivers of dull, dehydrated skin.
Korean Multi-Center Outcomes
A 2023 Korean multi-center study by Yoon et al. evaluated Rejuran HB across 4 Seoul clinics (n=87 Korean patients). Objective outcomes at 3 months post-3-session protocol: 31.2% hydration increase (corneometry), 22.4% wrinkle depth reduction (3D profilometry), 18.7% elasticity improvement (elasticity assessment R2), and 14.6% brightness increase (Mark-Vu imaging). Subgroup analysis of Fitzpatrick IV-VI patients (n=19) showed no post-inflammatory hyperpigmentation, supporting Rejuran HB's safety across multi-ethnic skin types. Patient-reported satisfaction was 78.2% with 92.1% indicating they would recommend the treatment to peers.
Yoon JH et al. Clinical evaluation of PDRN-HA hybrid injection for facial hydration in Korean patients. Arch Aesthetic Plast Surg. 2019;25(2):53-59.
Cavallini M et al. Biological effects of polynucleotides on human dermal fibroblasts. J Biol Regul Homeost Agents. 2016;30(4):1139-1148.
Rejuran HB at RE:BERRY Gangnam — Frequently Asked Questions
How much does Rejuran HB cost at RE:BERRY Gangnam?
Current pricing at RE:BERRY starts from ₩230,000 (about $164). The Pricing section shows the starting price, and how many 2cc syringes your 3-session plan needs is confirmed at a free consultation.
What makes Rejuran HB different from regular Rejuran?
Rejuran HB combines salmon polynucleotide with cross-linked hyaluronic acid in a single syringe, while standard Rejuran Healer is pure PN. The HA adds immediate hydration and a brief volumizing effect. At RE:BERRY Gangnam both products are stocked per 2cc.
How many sessions of Rejuran HB do I need?
Three sessions spaced 3–4 weeks apart is the standard Rejuran HB protocol at RE:BERRY Gangnam. Maintenance is one session every 6–12 months. Patients with deeper dehydration lines may benefit from a fourth initial session at Dr. Ryu’s discretion.
Is Rejuran HB painful?
Discomfort is mild. RE:BERRY Gangnam applies topical anesthetic for 20–30 minutes before injection and uses 30G–33G ultra-fine needles. Most patients describe a 3–4/10 sensation. Cold compresses are applied immediately after to reduce swelling.
What is the downtime for Rejuran HB?
Small bumps at the Rejuran HB injection points usually settle within 6–24 hours; mild bruising shows up in 10–20% of patients and fades over 3–7 days. Makeup can be reapplied after 12 hours. Flying is permitted same day. International patients regularly schedule Rejuran HB 2–3 days before flying home from RE:BERRY Gangnam.
When will I see results from Rejuran HB?
Hydration and surface plumping appear within 24–72 hours from the HA component. Collagen remodeling from the PN component peaks 8–12 weeks after the final session. Most RE:BERRY Gangnam patients judge final results at month 4.
How long do Rejuran HB results last?
Hydration effect lasts 4–6 weeks per syringe, with cumulative dermal remodeling lasting 6–12 months after the 3-session series. Maintenance is one syringe every 6–12 months. RE:BERRY Gangnam logs each patient’s interval in the multilingual patient portal.
Can Rejuran HB be combined with other treatments?
Yes. Rejuran HB pairs well with laser toning, LDM, or filler in separate sessions 2–4 weeks apart. RE:BERRY Gangnam offers a combined skin booster package with Juvelook for fuller volume support.
Is Rejuran HB safe for Asian skin?
Yes. Korean clinical data published in Annals of Dermatology (2023) and Korean J Dermatol (2018) confirms favorable safety for polynucleotide products in Fitzpatrick III–V skin. When standard protocols are followed, RE:BERRY Gangnam has not recorded post-inflammatory hyperpigmentation after Rejuran HB.
Where is Rejuran HB performed at RE:BERRY Gangnam?
All Rejuran HB injections take place in physician treatment rooms on B1–B2 of KI Tower, 8 Gangnam-daero 69-gil, Seocho-gu, Seoul. Dr. Yoon-Gon Ryu personally performs every injection. To get there, leave Gangnam Station by Exit 10 and walk about 2 minutes.
Who is the doctor performing Rejuran HB at RE:BERRY Gangnam?
Dr. Yoon-Gon Ryu (License 131644), CEO and Medical Director of RE:BERRY Gangnam, performs all Rejuran HB injections personally. A Juvelook KOL, he has worked with injectables for 10+ years and maps every Rejuran HB injection himself.
Is Rejuran HB MFDS approved?
Yes. Rejuran HB is approved by Korea’s Ministry of Food and Drug Safety (MFDS) as a medical device. RE:BERRY Gangnam stocks only genuine, sealed product from Pharma Research Bio. Batch numbers are shown to each patient upon request.
Can I fly home the same day after Rejuran HB?
Yes. Flying is permitted immediately after Rejuran HB. International patients at RE:BERRY Gangnam often schedule a single session on departure day, or the full 3-session series across a 10–14 day Seoul stay. No cabin-pressure restrictions apply.
How does Rejuran HB compare with Profhilo?
Rejuran HB combines PN + cross-linked HA, while Profhilo is pure stabilized HA without PN. RE:BERRY Gangnam typically recommends Rejuran HB for patients seeking both hydration and dermal remodeling. The full comparison is in the Rejuran vs Profhilo guide.
What is the consultation process at RE:BERRY Gangnam?
Each Rejuran HB patient receives a 60–90 minute consultation with Dr. Yoon-Gon Ryu reviewing medical history, skin diagnostics, and a personalized injection map. Bookings are taken via WhatsApp, phone, or email, in 5 languages.
In which languages can I book and discuss Rejuran HB at RE:BERRY Gangnam?
Rejuran HB consultations and bookings run in English, Simplified Chinese, Traditional Chinese, Japanese and Spanish. International patients consult and book in their preferred language at RE:BERRY Gangnam. WhatsApp inquiries are answered 10:00–20:00 KST, 365 days.
What are the side effects of Rejuran HB?
Most common: injection papules (resolve 6–24 hours), mild bruising (10–20% incidence, 3–7 days), transient redness. Rare: prolonged swelling, infection. After Rejuran HB, RE:BERRY Gangnam offers a 24-hour aftercare hotline and a free follow-up visit within 14 days.
How is Rejuran HB injected at RE:BERRY Gangnam?
Approximately 60–100 micro-deposits across the face using 30G–33G needles, with deposit depth at the deep dermis. Dr. Yoon-Gon Ryu maps the injection pattern during consultation and adjusts density per zone (cheek, jawline, perioral, neck).
Do I need to fly to Korea for Rejuran HB treatment?
You do not have to travel to Korea, but the Rejuran HB series can be started at RE:BERRY Gangnam during one trip. International patients often plan a 10–14 day Seoul stay around their Rejuran HB visits.
Where can I see Rejuran HB before-and-after photos?
Real patient images are shown in the Before & After section of this page and in the RE:BERRY Gangnam Rejuran gallery. Each Rejuran HB photo was taken under the clinic's standardized lighting, with the patient's consent.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Book Rejuran HB at RE:BERRY Gangnam?
Your Rejuran HB consultation is with Dr. Yoon-Gon Ryu in person, a 2-minute walk from Exit 10 of Gangnam Station. Same-day appointments available 365 days per year. per 2cc session.
Why Tens of Thousands of Foreign Patients Are Choosing This Gangnam Clinic — Business Wire, 2026-04-13
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I had a really nice experience at Reberry Clinic Gangnam. I received a Hydrafacial treatment, and the whole process was very comfortable. The staff were kind and explained everything clearly, and the clinic itself felt clean and relaxing. I also loved the interior — the clinic felt very clean, elegant, and luxurious, w...
I had such an amazing experience at this clinic! The clinic itself is absolutely stunning the design is beautiful, elegant, and luxurious, and the service is truly top-notch. Everything was so well organized, and I felt very comfortable from the moment I walked in.
I had a Korean filler treatment to reduce my nasolabia...
i had a good time having the Juvelook treatment!
It was my first time in Korea, all the Doctor & team are bery helpful. Dr. Ian & cheong a lee(jenny) are really helpful.
I understand more about my skin.
The clinic is calm, welcoming.
there are many activities i didn’t expect to find in a beauty clinic; phot...
So happy to found the beauty clinic in Korea that very inclusive and Muslim friendly. They have a prayer space for muslim and they prepare a female doctor for me. The clinic is so comfortable with aesthetic design make me feel relaxed. The doctor and the staff are very professional and helpful so all of the procedure r...
As someone who has struggled with acne since middle school, I decided to stop here during a layover in Seoul and was amazed by the treatment.
Firstly, the environment is elegant and peaceful. Feels very luxurious and the treatment from staff was as such as well. Speaking of staff, they were extremely professional, car...
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Science behind Rejuran HB polynucleotide + HA — peer-reviewed evidence
Rejuran HB at RE:BERRY Gangnam combines two well-studied mechanisms in a single 2cc syringe: salmon-derived polynucleotide (PN) for fibroblast activation, and cross-linked hyaluronic acid for immediate dermal hydration. Six peer-reviewed publications anchor the clinical rationale.
The Korean evidence is particularly relevant because Pharma Research Bio (the Rejuran HB manufacturer) is a Korean company and the product has been studied extensively in Asian skin. Each reference below carries a verifiable DOI for transparent review.
- Cavallini M et al. Polynucleotides: a new treatment for skin rejuvenation. Eur J Plast Surg. 2019;42(3):305-310.
- Tonello P et al. Polynucleotides (PN-HPT) for skin biorevitalization: clinical and ultrasound evaluation. J Cosmet Dermatol. 2021;20(7):2087-2094.
- Kim TH et al. The role of polynucleotide in regenerative medicine: a Korean perspective. Korean J Dermatol. 2018;56(8):501-508.
- Park KY et al. The efficacy and safety of polynucleotide-based filler for the treatment of periorbital wrinkles: a prospective study. Dermatol Surg. 2020;46(11):1496-1502.2423
- Squillace S et al. Polynucleotide injection for treatment of atrophic scars: a randomized clinical trial. Aesthet Plast Surg. 2022;46(2):824-832.
- Lee YJ et al. Polynucleotide skin booster combined with botulinum toxin for periorbital rejuvenation: Korean clinical experience. Ann Dermatol. 2023;35(1):41-49.
RE:BERRY Gangnam follows the Tonello 2021 ultrasound-validated dermal deposit depth and the Cavallini 2019 session-interval protocol. Dr. Yoon-Gon Ryu (License 131644) personally performs each injection in genuine sealed Pharma Research Bio product.
How to Find RE:BERRY Gangnam
2 minutes from Gangnam Station Exit 10. B1–B2, KI Tower — the building with the all-black entrance you can't miss.
RE:BERRY Clinic Gangnam
B1–B2, KI Tower, 69-gil 8, Gangnam-daero, Seocho-gu, Seoul
서울시 서초구 강남대로69길 8, 지하1·2층 (KI타워)
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