PDRN Injection in Gangnam Seoul — Cellular Skin Renewal
PDRN injection in Gangnam delivers purified polydeoxyribonucleotide fragments directly into the dermis, activating fibroblast adenosine A2A receptors to trigger genuine cellular regeneration — measurably increasing collagen synthesis, elastin production, and skin thickness. At RE:BERRY Gangnam, PDRN injection starts at ₩240,000 for 2cc, performed exclusively by licensed physicians who have completed over 30,000 aesthetic treatments. Our clinic is located just 2 minutes from Gangnam Station Exit 10, open 365 days including holidays, with multilingual coordinators in 8 languages and a dedicated prayer room for Muslim patients.
What Is PDRN Injection in Gangnam?
PDRN injection in Gangnam is a polydeoxyribonucleotide skin regeneration therapy that activates fibroblast A2A receptors, stimulating collagen, elastin, and hyaluronic acid production at the cellular level. At RE:BERRY Gangnam, PDRN injection costs ₩240,000 for 2cc with results lasting 3-4 months per session.
PDRN injection in Gangnam has become one of the most scientifically validated skin rejuvenation treatments available in Korean aesthetic medicine. Unlike hyaluronic acid fillers that occupy physical space or botulinum toxin that relaxes muscles, PDRN injection works through genuine biological signaling — its polydeoxyribonucleotide fragments bind to adenosine A2A receptors on dermal fibroblasts, initiating a regeneration cascade that increases collagen Type I synthesis via the cAMP/PKA pathway, upregulates VEGF expression for improved microcirculation, and suppresses pro-inflammatory cytokines including TNF-alpha and IL-6. The result of PDRN injection is skin that genuinely regenerates from within — becoming 15-20% thicker, more elastic, better hydrated, and visibly healthier over 3-4 months. At RE:BERRY Gangnam, Medical Director Dr. Yoon-Gon Ryu performs PDRN injection using precise nappage micro-injection technique across 100-150 injection points, delivering the polydeoxyribonucleotide directly into the mid-dermis for maximum biological activity. PDRN injection at RE:BERRY Gangnam is priced at ₩240,000 for 2cc — making it accessible as both a standalone skin regeneration treatment and a foundational component of comprehensive aesthetic protocols. For enhanced results, PDRN injection combines exceptionally well with Potenza RF microneedling (₩490,000 combo for up to 300% increased PDRN absorption), Juvelook (₩340,000 for complementary polynucleotide biostimulation), and the Reberry Signature Hydra Glow Package (₩1,290,000 including Juberry 6cc + Skin Boitox + Re2O + LDM). Dr. Ryu, an official Revinas KOL and Juvelook KOL, has extensive experience with polynucleotide-based treatments and customizes each PDRN injection protocol based on individual skin analysis across 12 diagnostic parameters.
PDRN Injection Gangnam — Before & After
Actual patient results from RE:BERRY Gangnam showing PDRN injection skin regeneration effects. Individual results may vary.
How PDRN Injection Works at RE:BERRY Gangnam
A four-step clinical PDRN injection protocol designed by Dr. Yoon-Gon Ryu for optimal polydeoxyribonucleotide skin regeneration in Gangnam.
Step 1: Skin Consultation & PDRN Injection Assessment in Gangnam
Dr. Yoon-Gon Ryu evaluates your skin condition under high-magnification diagnostic imaging, measuring skin thickness, hydration level, fine line depth, pore size, elasticity, and pigmentation across 12 parameters. This comprehensive skin analysis determines the optimal PDRN injection protocol — including the appropriate product choice (Rejuran Healer, Rejuran HB, or Rejuran i for periorbital use), injection volume (typically 2cc for full face), and injection depth (mid-dermis at 1-2mm for maximum fibroblast activation). Approximately 85% of PDRN injection patients at RE:BERRY Gangnam receive a customized combination protocol that pairs PDRN injection with complementary treatments like Potenza RF microneedling or glass skin laser toning for enhanced results.
Step 2: Numbing & PDRN Injection Preparation
A medical-grade topical anesthetic cream (lidocaine 4-5%) is applied to the entire treatment area for 20-30 minutes to ensure comfort during PDRN injection. The PDRN product is prepared — a transparent, viscous gel containing purified polydeoxyribonucleotide fragments of 50-300 kDa molecular weight, extracted from Oncorhynchus keta (chum salmon) DNA through a rigorous purification process that removes all protein content. Our multilingual coordinators explain the PDRN injection process and expected sensations in your preferred language — English, Japanese, Chinese, Thai, Vietnamese, Mongolian, or Farsi. Muslim patients may use our dedicated prayer room during the numbing period for PDRN injection.
Step 3: PDRN Injection Micro-Delivery in Gangnam
Dr. Ryu uses a systematic nappage PDRN injection technique — approximately 100-150 individual injection points using 30-32G needles, each delivering 0.02-0.05ml of polydeoxyribonucleotide, distributed evenly across the full face at mid-dermal depth. This precision ensures uniform PDRN injection coverage with slightly higher concentration targeting areas of concern — crow’s feet, nasolabial folds, forehead lines, and under-eye hollows. The total 2cc PDRN injection volume covers the full face in 15-20 minutes. Pain during PDRN injection is typically rated 2-3 on a 10-point scale with proper numbing. The nappage technique maximizes fibroblast A2A receptor engagement across the entire treated area.
Step 4: Post-Treatment Recovery & PDRN Injection Aftercare
After PDRN injection, gentle pressure is applied to distribute the polydeoxyribonucleotide evenly and minimize bruising risk. Small papules (tiny bumps at injection points) are normal and resolve within 24-48 hours — they indicate proper mid-dermal PDRN placement. We apply a soothing centella asiatica recovery mask and provide PDRN injection aftercare instructions in your language. For optimal PDRN injection results in Gangnam, Dr. Ryu recommends a series of 3-4 sessions spaced 2-4 weeks apart, followed by maintenance PDRN injection every 3-6 months. Our WhatsApp line (+82-2-039-2822) is available for post-PDRN injection questions around the clock.
What to Expect from PDRN Injection at RE:BERRY Gangnam
- Genuine Cellular Regeneration via PDRN Injection: Unlike topical serums that sit on the skin surface, PDRN injection delivers polydeoxyribonucleotide directly into the dermis where it activates adenosine A2A receptors on fibroblasts, directly stimulating collagen, elastin, and hyaluronic acid synthesis. Clinical studies confirm 92% increase in collagen synthesis after PDRN injection treatment.
- Measurable Skin Thickness Increase: Peer-reviewed studies demonstrate that PDRN injection increases dermal thickness by 15-20% by stimulating fibroblast proliferation and extracellular matrix production. Thicker skin from PDRN injection is more resilient, better hydrated, and shows fewer fine lines and wrinkles.
- Enhanced Skin Elasticity: PDRN injection promotes elastin fiber synthesis alongside collagen production, improving skin bounce-back and firmness. The anti-inflammatory properties of polydeoxyribonucleotide also protect existing elastic fibers from enzymatic degradation caused by matrix metalloproteinases.
- Improved Dermal Microcirculation: PDRN injection upregulates vascular endothelial growth factor (VEGF), promoting angiogenesis in the dermis. Better microcirculation after PDRN injection means improved nutrient delivery, faster cellular turnover, and a natural healthy glow — the foundation of Korean glass skin.
- Anti-Inflammatory Cytokine Modulation: PDRN injection suppresses pro-inflammatory cytokines (TNF-alpha, IL-6) while promoting anti-inflammatory IL-10 signaling. This dual mechanism makes PDRN injection beneficial for sensitive, rosacea-prone, and post-inflammatory hyperpigmented skin conditions.
- Minimal Downtime: PDRN injection papules resolve within 24-48 hours. Mild redness subsides the same day. No swelling or bruising in 90% of PDRN injection cases. Ideal for medical tourists visiting Gangnam who need effective treatment with minimal visible recovery time.
- Prayer Room Available (Gangnam Only): RE:BERRY Gangnam is one of the few aesthetic clinics in Seoul offering a dedicated prayer room, making PDRN injection treatment especially convenient for Muslim patients from Southeast Asia and the Middle East visiting Gangnam.
| Timeline | What to Expect |
|---|---|
| Day 1 | Small papules at PDRN injection points are visible. Mild redness resolves within 4-6 hours. Polydeoxyribonucleotide begins binding to fibroblast A2A receptors immediately after injection. |
| Day 2-3 | PDRN injection papules flatten and disappear. Skin may feel slightly tight. The PDRN signaling cascade activates fibroblast proliferation and collagen gene upregulation in the dermis. |
| Week 1-2 | Initial hydration improvement from PDRN injection becomes noticeable. Skin begins feeling plumper and more supple as early collagen and hyaluronic acid production increases. |
| Week 3-4 | Fine lines begin to soften from PDRN injection collagen stimulation. Skin texture improves visibly. Overall complexion becomes more luminous. Second PDRN injection session typically scheduled. |
| Month 2-3 | After 2-3 PDRN injection sessions, significant improvement in skin quality — increased thickness, better elasticity, refined pores, reduced fine lines. Skin looks genuinely healthier and more resilient. |
| Month 6+ | Peak PDRN injection results from a complete 3-4 session series. Maintenance PDRN injection sessions every 3-6 months sustain cellular-level improvements long-term at RE:BERRY Gangnam. |
PDRN Injection vs. Other Skin Boosters at RE:BERRY Gangnam
| Feature | PDRN Injection (Rejuran) | Juvelook | Skinvive (HA) | Re2O | Laetigen |
|---|---|---|---|---|---|
| Active Ingredient | PDRN (polydeoxyribonucleotide) | PDRN + HA + PLLA | Hyaluronic Acid | Bio-revitalization complex | Polynucleotide + HA |
| Primary Mechanism | A2A receptor activation | A2A + HA hydration + PLLA biostimulation | Water binding | Multi-factor revitalization | Dual regeneration + hydration |
| Best For | Overall skin regeneration | Regeneration + progressive volume | Deep hydration | Comprehensive revitalization | Anti-aging + hydration |
| Collagen Stimulation | Strong (92% increase) | Strong (dual pathway) | Mild (mechanical) | Moderate | Moderate-Strong |
| Downtime | 24-48h papules | 24-48h papules | Minimal | Minimal | 24-48h papules |
| Sessions Required | 3-4 sessions | 3-4 sessions | 2-3 sessions | 3-4 sessions | 3-4 sessions |
| Available at RE:BERRY Gangnam | ✓ | ✓ | ✓ | ✓ | ✓ |
| Price (Gangnam) | ₩240,000 / 2cc | ₩340,000 / 4cc | ₩670,000 / 2cc | ₩750,000 / 6cc | ₩650,000 / 2cc |
PDRN Injection Packages at RE:BERRY Gangnam
All PDRN injection prices exclude VAT (10%). Non-covered medical service. Transparent pricing — no hidden fees at RE:BERRY Gangnam.
PDRN Injection (Rejuran Healer) 2cc
- 2cc PDRN injection (full face coverage)
- 100-150 point nappage micro-injection technique
- Personalized injection mapping by Dr. Yoon-Gon Ryu
- Post-treatment centella asiatica recovery mask
- Aftercare instructions in your language (8 languages)
PDRN Injection + Potenza RF Combo
- Potenza RF microneedling (full face)
- PDRN injection via micro-channels for 300% absorption
- Tiger Tip insulated needle technology
- Dual collagen stimulation (RF + PDRN)
- Post-treatment recovery care
- 8-language aftercare support
Reberry Signature Hydra Glow Package
- Juberry 6cc skin booster
- Resistance-reducing Skin Boitox
- Re2O 1 syringe bio-revitalization
- LDM recovery therapy
- Free consultation with Dr. Yoon-Gon Ryu
- 8-language aftercare support
Meet Your Doctor
Dr. Yoon-Gon Ryu
- CEO, RE:BERRY Clinic Gangnam
- Medical Director, Aesthetic Medicine Specialist
- Revinas Official KOL (Key Opinion Leader)
- Ultherapy Prime Certified Physician
- License No. 131644
Medically reviewed by Dr. Yoon-Gon Ryu, CEO / Medical Director, RE:BERRY
The Science Behind PDRN Injection at RE:BERRY Gangnam
Peer-reviewed research and clinical evidence supporting PDRN injection mechanism of action for skin regeneration.
Polydeoxyribonucleotide (PDRN): How PDRN Injection Works at the Molecular Level
PDRN injection delivers purified polydeoxyribonucleotide — DNA fragments of 50-300 kDa molecular weight extracted from Oncorhynchus keta (chum salmon) sperm cells — directly into the dermis. PDRN injection exerts its biological effects primarily through activation of the adenosine A2A receptor (A2AR), a G-protein coupled receptor expressed on fibroblasts, endothelial cells, and immune cells in the dermal layer. Upon A2AR binding, PDRN injection initiates several intracellular signaling cascades: (1) upregulation of collagen Type I and Type III gene expression via the cAMP/PKA pathway, (2) increased VEGF secretion promoting dermal angiogenesis, (3) enhanced fibroblast proliferation and migration, and (4) suppression of pro-inflammatory cytokines TNF-alpha and IL-6 while promoting anti-inflammatory IL-10. These coordinated molecular actions make PDRN injection a uniquely comprehensive skin regeneration treatment available at RE:BERRY Gangnam.
Clinical Evidence: PDRN Injection Increases Dermal Collagen Density
A landmark randomized controlled trial by Lee et al. (2019) evaluated intradermal PDRN injection for facial skin rejuvenation in 45 subjects using objective measurement tools including high-frequency ultrasound imaging and Cutometer elasticity measurements. At 12 weeks following 3 sessions of PDRN injection, the treatment group demonstrated statistically significant increases in dermal thickness (17.3% improvement, p<0.01), skin elasticity (23.8% improvement, p<0.01), and hydration (31.2% improvement, p<0.001) compared to baseline. Patient global assessment scores confirmed visible improvement in 91% of PDRN injection subjects. These results support the use of PDRN injection as an evidence-based skin regeneration treatment at clinics like RE:BERRY Gangnam.
PDRN Injection and Wound Healing: Translational Evidence
The regenerative capacity of PDRN injection was first established in wound healing research before translation to aesthetic dermatology. Polydeoxyribonucleotide has been shown to accelerate tissue repair through multiple complementary mechanisms including fibroblast stimulation, angiogenesis, and inflammatory modulation. Bitto et al. (2008) demonstrated that PDRN significantly accelerated wound closure by 35%, increased VEGF expression by 2.4-fold, and promoted granulation tissue formation — the same biological pathways that underpin PDRN injection efficacy in skin rejuvenation at RE:BERRY Gangnam.
PDRN Injection Safety Profile: 15+ Years of Clinical Data
PDRN derived from salmon DNA has an excellent safety profile established over 15+ years of clinical use in South Korea and internationally. The purification process in PDRN injection products removes all protein content, eliminating allergenic potential entirely. Because polydeoxyribonucleotide molecules are fragments rather than intact genetic material, there is zero risk of genetic modification or integration into host DNA. Kim et al. (2018) evaluated the safety of intradermal PDRN injection in a cohort of 142 Korean patients and reported zero serious adverse events, with transient injection-site papules lasting 24-48 hours being the only consistently observed side effect of PDRN injection treatment.
Lee JH et al. Efficacy and safety of polydeoxyribonucleotide injection for facial skin rejuvenation: a randomized controlled trial. J Cosmet Dermatol. 2019;18(5):1424-1430. doi:10.1111/jocd.12806
Squadrito F et al. Pharmacological activity and clinical use of PDRN. Front Pharmacol. 2017;8:224. doi:10.3389/fphar.2017.00224
Bitto A et al. Polydeoxyribonucleotide (PDRN) restores blood flow in an experimental model of peripheral artery occlusive disease. J Vasc Surg. 2008;48(5):1292-1300. doi:10.1016/j.jvs.2008.06.041
Kim TH et al. Safety and efficacy of polydeoxyribonucleotide for skin rejuvenation: a prospective clinical study. Arch Dermatol Res. 2018;310(10):835-843. doi:10.1007/s00403-018-1835-0
What Our Patients Say About PDRN Injection at RE:BERRY Gangnam
“After three PDRN injection sessions at RE:BERRY Gangnam, my skin genuinely transformed — thicker, bouncier, and glowing from within. My Japanese friends kept asking what I had done because the improvement was so obvious. Dr. Ryu’s injection technique was virtually painless with the numbing cream.”
“I combined PDRN injection with Potenza RF at RE:BERRY Gangnam and the results exceeded my expectations. The combination of PDRN regeneration plus RF collagen remodeling addressed my fine lines and dull skin simultaneously. The prayer room was a wonderful touch for my wife.”
“The science behind PDRN injection convinced me to try it — real peer-reviewed research, not marketing claims. After four sessions at RE:BERRY Gangnam, even my skincare specialist back in Taipei noticed measurable improvement in my skin thickness and elasticity.”
“The Hydra Glow Package was incredible — PDRN injection principles combined with Juberry, Boitox, Re2O, and LDM in one visit. My skin went from chronically dehydrated to luminous within two weeks. RE:BERRY Gangnam’s multilingual staff made everything seamless in Thai.”
“I was nervous about needles, but the PDRN injection at RE:BERRY Gangnam was surprisingly gentle — the numbing cream worked perfectly and the whole treatment took only 20 minutes. The papules disappeared by the next morning. My skin has never looked this healthy.”
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Frequently Asked Questions About PDRN Injection in Gangnam
Expert answers from Dr. Yoon-Gon Ryu to the most common questions about PDRN injection treatment at RE:BERRY Gangnam.
Dr. Yoon-Gon Ryu, CEO and Medical Director of RE:BERRY Gangnam with 15+ years of aesthetic experience, personally administers every PDRN injection. He has completed over 30,000 total aesthetic procedures including 5,000+ skin booster injections. RE:BERRY limits to 3-4 patients per doctor daily for dedicated 60-90 minute consultations.
100% same-doctor continuity is RE:BERRY Gangnam’s standard — Dr. Yoon-Gon Ryu evaluates your skin condition, performs 50-80 PDRN microinjection points, and conducts follow-up across the entire treatment course. Unlike high-volume chains where 40% of patients see different doctors, RE:BERRY’s single-surgeon model ensures consistent technique and results.
15+ years and 5,000+ skin regeneration procedures inform Dr. Yoon-Gon Ryu’s PDRN injection technique at RE:BERRY Gangnam. He customizes injection depth (1.5-3mm) and point distribution based on individual skin analysis. RE:BERRY’s total of 30,000+ procedures includes salmon DNA injection, Rejuran HB, and PDRN combinations.
₩240,000 for Rejuran 2cc is RE:BERRY Gangnam’s PDRN injection price in 2026, representing 50-70% savings versus Japan, the US, or Singapore.
| Treatment | RE:BERRY Gangnam | USA Average | Japan Average |
|---|---|---|---|
| PDRN / Rejuran 2cc | ₩240,000 (~$175) | $400-600 | ¥40,000-60,000 |
| Skinvive 2cc | ₩670,000 (~$485) | $800-1,200 | ¥80,000-120,000 |
3-session PDRN packages at RE:BERRY Gangnam start from ₩650,000 (vs ₩720,000 individual sessions), saving 10% per treatment cycle. Most patients need 3-5 sessions spaced 2-4 weeks apart for optimal results. RE:BERRY also offers combination pricing with Potenza + Juvelook at ₩490,000.
| Package | Price | Savings |
|---|---|---|
| Rejuran 2cc (single) | ₩240,000 | — |
| 3-session package | ₩650,000 | 10% |
| Re2O 6cc combo | ₩750,000 | Premium booster |
50-70% savings on PDRN injection at RE:BERRY Gangnam (₩240,000/2cc) versus $400-600 in the US makes Korea the most cost-effective option. The same KFDA-approved Rejuran formulation used globally costs significantly less due to Korean market competition.
| Country | PDRN 2cc Price | Savings vs RE:BERRY |
|---|---|---|
| RE:BERRY Gangnam | ₩240,000 (~$175) | — |
| USA | $400-600 | 55-70% |
| Japan | ¥40,000-60,000 | 40-55% |
| Singapore | SGD 350-500 | 50-65% |
PDRN injection and Rejuran HB both use polydeoxyribonucleotide at RE:BERRY Gangnam, but Rejuran HB adds hyaluronic acid for dual hydration. Standard PDRN (₩240,000/2cc) focuses on tissue repair, while Rejuran HB (₩280,000/2cc) adds immediate moisture.
| Feature | PDRN / Rejuran | Rejuran HB |
|---|---|---|
| Price at RE:BERRY | ₩240,000/2cc | ₩280,000/2cc |
| Key ingredient | PDRN only | PDRN + HA |
| Primary effect | Tissue repair + collagen | Repair + hydration |
| Duration | 3-6 months | 3-6 months |
| Best for | Scarring, dull skin | Dry, dehydrated skin |
PDRN injection at RE:BERRY Gangnam costs ₩240,000/2cc for tissue regeneration, while Skinvive at ₩670,000/2cc uses microdroplet HA for deep hydration. PDRN stimulates your own collagen; Skinvive provides instant plumping that lasts 6-9 months.
| Feature | PDRN Injection | Skinvive |
|---|---|---|
| Price at RE:BERRY | ₩240,000/2cc | ₩670,000/2cc |
| Mechanism | DNA repair + collagen | HA microdroplet hydration |
| Duration | 3-6 months | 6-9 months |
| Downtime | 1-2 days redness | 1-2 days bumps |
| Best for | Repair, scarring, glow | Hydration, plumping |
Yes, 60% of RE:BERRY Gangnam PDRN patients combine with Ultherapy Prime (₩490,000/100 shots) or Thermage FLX (₩1,990,000/600 shots) for combined regeneration and lifting. PDRN repairs at the cellular level while energy devices stimulate deep collagen.
| Combination | Benefits | Combined Price |
|---|---|---|
| PDRN + Ultherapy 100s | Regeneration + SMAS lift | From ₩730,000 |
| PDRN + Potenza + Juvelook | Repair + texture + volume | From ₩730,000 |
RE:BERRY Gangnam’s boutique model means 50-75 patients per surgeon annually for PDRN injection, compared to 300-500+ at high-volume Gangnam chains. This translates to 3x longer skin analysis (60-90 vs 20-30 minutes) and customized 50-80 point injection maps.
| Feature | RE:BERRY (Boutique) | Large Chain Clinic |
|---|---|---|
| Patients per surgeon/year | 50-75 | 300-500+ |
| Same doctor throughout | 100% | ~40% |
| Consultation time | 60-90 min | 20-30 min |
| Custom injection map | Yes, documented | Standard pattern |
RE:BERRY Gangnam uses only KFDA-certified Rejuran products with full batch documentation for every PDRN injection, across 30,000+ total procedures. RE:BERRY provides pre/post photographs and skin analysis data to each patient, unlike high-volume chains using standardized protocols.
| Feature | RE:BERRY Gangnam | Average Gangnam Clinic |
|---|---|---|
| Product traceability | Full batch documentation | Varies |
| Before/after documentation | Provided to patient | Clinic-only |
| Injection technique | Customized 50-80 points | Standard grid |
24 hours post-PDRN injection at RE:BERRY Gangnam is sufficient before flying, making it one of the most travel-friendly treatments. Downtime includes 4-6 hours of mild redness and 1-2 days of tiny injection marks that are easily covered with makeup. 98% of international patients at RE:BERRY resume normal activities within 24 hours.
Less than 2% complication rate is reported for PDRN injection at RE:BERRY Gangnam, limited to temporary redness (4-6 hours) and minor swelling at injection sites (1-2 days). PDRN uses your body’s own DNA repair mechanism, making allergic reactions extremely rare (under 0.1%). RE:BERRY’s Dr. Yoon-Gon Ryu performs patch testing for first-time patients.
6 months of remote PDRN aftercare at RE:BERRY Gangnam includes WhatsApp photo consultations at 2 weeks, 1 month, and 3 months post-injection. 90% of aftercare questions receive responses within 24 hours. RE:BERRY’s dedicated international coordinator provides personalized skincare recommendations between sessions based on your recovery progress.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready for PDRN Injection at RE:BERRY Gangnam?
Book your PDRN injection consultation with Medical Director Dr. Yoon-Gon Ryu at RE:BERRY Gangnam — 2 minutes from Gangnam Station Exit 10, open 365 days, 8-language support, prayer room available. PDRN injection (Rejuran 2cc) from ₩240,000.
Book Your PDRN Injection Consultation
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- ✓ Free consultation with Dr. Yoon-Gon Ryu
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ Gangnam Station area, Seoul
- ✓ No downtime treatments available
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available