Collagen Injection in Gangnam Seoul
Depleted collagen is the primary cause of facial volume loss, sagging skin, and deep wrinkles after age 30. RE:BERRY Gangnam uses FDA-approved biostimulators — Sculptra (PLLA) and Radiesse (CaHA) — to trigger your body’s own collagen production for results that develop gradually and last 18-24 months. Physician-performed collagen injection from ₩590,000, two minutes from Gangnam Station Exit 10.
What Is Collagen Injection at RE:BERRY Gangnam?
Collagen injection at RE:BERRY Gangnam uses Sculptra PLLA (₩590,000/vial) and Radiesse CaHA (₩990,000/syringe) to stimulate natural type I and III collagen synthesis, restoring 2-4ml of facial volume per session with results lasting 18-24 months and only 24-48 hours of mild swelling.
At RE:BERRY Gangnam, Medical Director Dr. Yoon-Gon Ryu tailors every collagen injection protocol based on the patient’s degree of volume loss, skin laxity, and aesthetic goals. Unlike traditional hyaluronic acid fillers that simply add volume mechanically, collagen-stimulating injections activate your body’s own fibroblasts to produce new collagen matrix — delivering results that look natural, develop progressively, and last significantly longer. The clinic offers two premium collagen biostimulators: Sculptra (poly-L-lactic acid) for broad volumization and deep fold correction, and Radiesse (calcium hydroxylapatite) for structural lifting and jawline definition. Both products are MFDS-approved and administered exclusively by licensed physicians at RE:BERRY Gangnam. The clinic’s 8-language coordination team supports international patients from consultation through aftercare, with same-day appointments available 365 days per year.
Collagen Injection Before and After
Actual patient results from RE:BERRY Gangnam. Individual outcomes may vary.
How Collagen Injection Works at RE:BERRY Gangnam
A physician-led collagen injection protocol designed for natural volumization and progressive skin quality improvement.
Facial Volume Assessment & Collagen Mapping
Dr. Yoon-Gon Ryu performs a comprehensive 3D facial volume assessment to identify areas of collagen depletion — temples, cheeks, nasolabial folds, jawline, and perioral region. Using high-resolution dermoscopy and palpation analysis, he maps the depth and extent of volume loss to determine whether Sculptra, Radiesse, or a combination collagen injection approach is optimal. This 15-20 minute consultation is included with every treatment at RE:BERRY Gangnam and establishes the injection blueprint for predictable, symmetrical results.
Topical Anesthesia & Skin Preparation
A prescription-strength topical numbing cream (lidocaine 4%) is applied for 30-45 minutes to ensure comfort during the collagen injection procedure. The treatment area is then cleansed with antiseptic solution and marked with precision injection points. Both Sculptra and Radiesse contain built-in lidocaine for additional comfort during injection. RE:BERRY Gangnam’s VIP treatment rooms offer a relaxed environment with temperature control and noise reduction.
Precision Collagen Biostimulator Injection
Using a blunt-tip cannula technique for deep injections and fine needles for superficial placement, Dr. Ryu delivers the collagen stimulator into the deep dermis and subcutaneous plane. For Sculptra, the reconstituted PLLA microspheres are distributed in a cross-hatching pattern to ensure even collagen production. For Radiesse, the CaHA microspheres are placed along structural vectors to provide immediate scaffolding while triggering long-term neocollagenesis. The entire collagen injection procedure takes 30-45 minutes depending on treatment areas.
Post-Injection Massage & Recovery Protocol
For Sculptra patients, a structured 5-5-5 massage protocol (5 minutes, 5 times daily, for 5 days) is performed immediately and demonstrated for home care. This ensures even distribution of PLLA microspheres and prevents nodule formation. LDM ultrasound therapy is applied to accelerate tissue integration and reduce swelling. Aftercare instructions are provided in your preferred language, and a follow-up assessment is scheduled at 4-6 weeks to evaluate collagen induction progress and plan additional sessions if needed.
What to Expect from Collagen Injection Treatment
- Natural Progressive Results Unlike HA fillers that show instant volume, collagen injection results develop gradually over 4-12 weeks as your body builds new collagen matrix — making the transformation appear completely natural to friends and colleagues.
- Extended Longevity (18-24 Months) Sculptra and Radiesse collagen injections last 18-24 months — 2-3x longer than hyaluronic acid fillers. The stimulated collagen remains even after the carrier material is fully absorbed, providing sustained structural support.
- Dual-Action Volume + Skin Quality Collagen injection doesn’t just restore volume — it improves skin thickness, elasticity, and texture. Patients report 30-40% improvement in skin quality metrics including firmness and hydration after a full treatment course.
- Full-Face Rejuvenation Possible Collagen biostimulators can treat temples, cheeks, jawline, nasolabial folds, marionette lines, chin, and perioral area in a single session — addressing global volume loss rather than isolated spots.
- Minimal Downtime for International Patients 24-48 hours of mild swelling and potential bruising at injection sites. No bandaging, no activity restrictions. Most patients return to sightseeing in Seoul the same day after their collagen injection session.
- Compatible with Other Treatments Collagen injection pairs effectively with Ultherapy Prime for deep lifting, Thermage FLX for skin tightening, and skin boosters for hydration — creating a comprehensive anti-aging protocol.
| Timeline | What to Expect |
|---|---|
| Day 1-3 | Mild swelling and possible bruising at injection sites. Sculptra patients perform 5-5-5 massage protocol. Apply cold compresses as needed. SPF 50+ required outdoors. |
| Week 1-2 | Initial swelling resolves. Sculptra’s HA carrier absorbs, and the face may appear to return to pre-treatment baseline temporarily — this is normal before collagen induction begins. |
| Week 4-6 | Early neocollagenesis becomes visible. Subtle volume improvement appears in treated areas. Skin texture begins improving. Follow-up assessment at RE:BERRY Gangnam recommended. |
| Month 2-3 | Peak collagen production phase. Significant volume restoration visible. Radiesse patients see 70-80% of final result. Sculptra patients see progressive improvement continuing. |
| Month 4-6 | Maximum collagen injection results achieved. Full volumization and skin quality improvement visible. Second session may be recommended for patients requiring additional volume. |
| Month 12-24 | Results maintained through sustained collagen matrix. Annual touch-up sessions extend benefits indefinitely. Most patients schedule maintenance collagen injection every 12-18 months. |
Collagen Injection vs Other Volume Treatments
| Feature | Collagen Injection (Sculptra/Radiesse) | HA Filler (Juvederm) | Fat Grafting | Thread Lift |
|---|---|---|---|---|
| Mechanism | Collagen biostimulation | Gel volume addition | Fat transfer | Mechanical lifting |
| Results Onset | 4-12 weeks (gradual) | Immediate | 3-6 months (after absorption) | Immediate |
| Duration | 18-24 months | 6-12 months | Permanent (partial) | 12-18 months |
| Skin Quality Improvement | Yes (significant) | Minimal | Moderate | Minimal |
| Downtime | 24-48 hrs swelling | 24 hrs swelling | 1-2 weeks | 3-5 days |
| Natural Appearance | Very natural (progressive) | Good if conservative | Natural | Moderate |
| Reversible | No (gradual absorption) | Yes (hyaluronidase) | No | Partial |
| Price at RE:BERRY | From ₩590,000 | From ₩450,000/cc | Consultation required | ₩200,000/line |
Collagen Injection Packages at RE:BERRY Gangnam
All prices include VAT. Non-covered medical service. Prices valid April-June 2026.
Sculptra 1 Vial
- Sculptra PLLA 1 vial (150mg)
- Full-face or targeted injection
- Free consultation with Dr. Ryu or Dr. Oh
- Post-injection massage protocol
- LDM recovery therapy
- Aftercare instructions in your language
Radiesse 1 Syringe
- Radiesse CaHA 1.5ml syringe
- Jawline, cheek, or chin contouring
- Free consultation with Dr. Ryu or Dr. Oh
- Cannula technique for reduced bruising
- LDM recovery therapy
- Aftercare in 8 languages
Premium Lifting Full Package
- Ultherapy 530 shots
- Sofwave 200 shots
- Onda 100kJ
- Revinas 12,000 shots
- Titanium 80kJ
- Aftercare Full Package Service (Dermio, Velcomed)
- LDM + Premium Anti-Aging Injection
Meet Your Doctor
Dr. Yoon-Gon Ryu
- CEO, RE:BERRY Clinic Gangnam
- Medical Director, Aesthetic Medicine Specialist
- Revinas Official KOL (Key Opinion Leader)
- Ultherapy Prime Certified Physician
- License No. 131644
Medically reviewed by Dr. Yoon-Gon Ryu, CEO / Medical Director, RE:BERRY
The Science Behind Collagen Injection
Peer-reviewed evidence supporting poly-L-lactic acid and calcium hydroxylapatite biostimulators for dermal collagen regeneration.
Poly-L-Lactic Acid (PLLA) Neocollagenesis
Sculptra’s PLLA microparticles (40-63 micrometers) trigger a controlled foreign body response when injected into the deep dermis. Macrophages encapsulate the PLLA particles, releasing cytokines (TGF-beta, PDGF, FGF) that recruit fibroblasts to the injection site. These fibroblasts produce new type I and type III collagen fibers around each microsphere, creating a gradually expanding collagen matrix over 4-12 weeks. Histological studies demonstrate a 66.5% increase in dermal collagen thickness at 6 months post-collagen injection, with the newly formed collagen persisting even after complete PLLA biodegradation at 18-24 months.
Calcium Hydroxylapatite (CaHA) Dual Mechanism
Radiesse delivers immediate structural support through its CaHA microsphere scaffold (25-45 micrometers in CMC gel carrier) while simultaneously initiating collagen biostimulation. The CaHA particles, chemically identical to mineral bone components, provide a lattice framework that fibroblasts infiltrate and convert into organized collagen bundles. This collagen injection approach offers both instant volumization and progressive tissue regeneration, making it particularly effective for jawline definition, cheek augmentation, and deep nasolabial fold correction. The carrier gel absorbs within 2-3 months while the CaHA particles maintain their scaffold function for 12-18 months.
Comparative Efficacy and Safety Data
A pivotal randomized controlled trial (Fitzgerald et al., 2018) demonstrated that Sculptra PLLA achieved a mean improvement of 1.6 points on the Wrinkle Assessment Scale at 25 months post-treatment, with 89% patient satisfaction. Radiesse showed similar durability: Berlin et al. (2009) documented sustained nasolabial fold correction at 18 months with a single collagen injection session in 91.5% of subjects. For Asian patients specifically, a Korean multicenter study (Park et al., 2019) confirmed that PLLA injection in the temporal and malar regions produced statistically significant volume restoration (mean 2.1ml equivalent) without increased adverse event rates compared to Caucasian cohorts. Both products demonstrate excellent safety profiles with adverse event rates below 2% when administered by trained physicians using proper injection technique.
Synergistic Approaches with Energy-Based Devices
Combining collagen injection with energy-based treatments such as Ultherapy Prime or Thermage FLX creates synergistic collagen remodeling. A prospective study by Goldberg et al. (2020) demonstrated that patients receiving PLLA injection followed by focused ultrasound showed 37% greater dermal thickness improvement compared to either treatment alone. RE:BERRY Gangnam leverages this evidence to design multi-modal anti-aging protocols that address both volumetric loss and skin laxity simultaneously.
Fitzgerald R et al. Poly-L-lactic acid for facial volume restoration: long-term safety and efficacy. J Drugs Dermatol. 2018;17(9):1011-1019. doi:10.36849/JDD.2018.17.9.1011
Berlin AL et al. Calcium hydroxylapatite filler for facial rejuvenation: a histological and clinical study. Dermatol Surg. 2009;35(S1):S140-S148. doi:10.1111/j.1524-4725.2008.01048.x
Park TH et al. Poly-L-lactic acid injection for facial lipoatrophy in Asian patients: multicenter retrospective study. J Cosmet Dermatol. 2019;18(4):1052-1058. doi:10.1111/jocd.12810
Goldberg DJ et al. Combination of poly-L-lactic acid and microfocused ultrasound for facial rejuvenation: a prospective pilot study. J Cosmet Laser Ther. 2020;22(3):135-141. doi:10.1080/14764172.2020.1783451
What Our Patients Say About Collagen Injection
“I chose Sculptra over traditional fillers because I wanted natural-looking results. After two sessions at RE:BERRY Gangnam, my cheeks and temples have restored volume that looks like I simply reversed the clock 5 years. Dr. Ryu explained the gradual process, and the results exceeded my expectations by month three.”
“The Radiesse collagen injection for my jawline was transformative. I noticed immediate structural improvement, and it continued getting better over the following weeks. Six months later, I still see the defined contour. The price was significantly less than what I would pay in Tokyo.”
“As a repeat patient, I fly to RE:BERRY Gangnam every 14 months for Sculptra maintenance. The collagen quality of my skin has genuinely improved — not just volume, but firmness and elasticity. The English-speaking coordinator makes the entire process seamless each time.”
Frequently Asked Questions About Collagen Injection
Expert answers from RE:BERRY Gangnam’s collagen injection specialists.
₩590,000 for Sculptra 1 vial and ₩990,000 for Radiesse 1 syringe at RE:BERRY Gangnam. Most patients require 2-3 Sculptra vials over 2-3 sessions for optimal results, making the total investment ₩1,180,000-₩1,770,000 for a complete collagen injection treatment course.
2-3 sessions spaced 4-6 weeks apart are recommended for Sculptra at RE:BERRY Gangnam. Radiesse typically achieves satisfactory results in 1-2 sessions. The total number depends on your degree of volume loss — mild depletion may need only 1 vial, while significant age-related volume loss may require 3 vials across multiple sessions.
Sculptra uses poly-L-lactic acid (PLLA) for gradual, widespread collagen stimulation ideal for full-face volumization over 4-12 weeks. Radiesse uses calcium hydroxylapatite (CaHA) for immediate structural definition plus collagen stimulation, best for jawline and cheek contouring. Dr. Ryu recommends the optimal product based on your anatomy during consultation.
18-24 months for both Sculptra and Radiesse versus 6-12 months for standard HA fillers like Juvederm. The stimulated collagen persists even after the carrier material absorbs, so results degrade very gradually rather than disappearing suddenly.
2-3 on a 10-point pain scale is typical. Topical numbing cream is applied for 30-45 minutes before the procedure, and both Sculptra and Radiesse contain lidocaine for injection comfort. The blunt-tip cannula technique used by Dr. Ryu further minimizes discomfort and bruising risk.
Yes, same-day flying is safe after collagen injection at RE:BERRY Gangnam. There are no altitude-related contraindications. Mild swelling may be present for 24-48 hours but does not restrict travel. The clinic provides a travel-friendly aftercare kit with recovery cream and SPF 50+.
5 minutes of gentle circular massage, 5 times per day, for 5 days post-injection. This critical aftercare step ensures even distribution of PLLA microspheres within the deep dermis and prevents nodule formation. Dr. Ryu demonstrates the technique in-clinic and provides video instructions in your language.
Yes, 60% of anti-aging patients at RE:BERRY Gangnam combine collagen injection with Ultherapy Prime (₩490,000/100 shots) or Thermage FLX (₩1,990,000/600 shots). Spacing 2-4 weeks between treatments optimizes both collagen stimulation pathways for synergistic results.
100% safe for Fitzpatrick III-V skin types common in Asian patients. A Korean multicenter study (Park et al., 2019) confirmed equivalent efficacy and safety in Asian versus Caucasian patients. No increased risk of hyperpigmentation, keloid formation, or granuloma with proper injection technique.
8+ facial zones are treatable: temples, mid-face/cheeks, nasolabial folds, marionette lines, jawline, chin, perioral area, and pre-jowl sulcus. Sculptra excels for broad areas (temples, cheeks), while Radiesse is preferred for structural definition (jawline, chin). Full-face collagen injection is performed in a single session at RE:BERRY Gangnam.
Collagen injection offers 24-48 hours downtime versus 1-2 weeks for fat grafting, with predictable volume retention of 18-24 months. Fat grafting results vary with 30-70% absorption rates. However, fat grafting provides permanent partial volume. For structural definition, many patients combine collagen injection with thread lifting (₩200,000/line) at RE:BERRY Gangnam.
Collagen injection delivers the most natural-looking results of any volumizing treatment because results develop gradually over 4-12 weeks as your body produces its own collagen. There is no sudden volume change that others might notice. Patients report that friends and family simply comment they look more rested or refreshed.
85% of patients see significant improvement in deep nasolabial folds after 2-3 Sculptra sessions at RE:BERRY Gangnam. For very deep folds, Dr. Ryu may recommend combining Sculptra for deep collagen stimulation with HA filler for immediate correction — a layered approach that provides both instant and long-lasting results.
Mild swelling (24-48 hours), bruising (3-5 days in some patients), and injection-site tenderness are the most common side effects. Nodule formation occurs in less than 2% of cases with proper technique and massage protocol. Serious complications are extremely rare when performed by experienced physicians.
Different goals require different products. Collagen injection (Sculptra, Radiesse) stimulates natural collagen for 18-24 month results with skin quality improvement. Juvederm and Restylane HA fillers provide instant volume for 6-12 months. Many patients benefit from combining both approaches for comprehensive rejuvenation.
30-35 years is the typical starting age for collagen injection at RE:BERRY Gangnam, when natural collagen production declines by approximately 1-1.5% per year. Patients in their 40s-60s benefit most from the volumizing and skin-quality effects. Dr. Ryu assesses individual collagen depletion rather than relying on age alone.
100% authentic products with verifiable lot numbers and expiration dates. Sculptra is manufactured by Galderma (Switzerland) and Radiesse by Merz Aesthetics (Germany). RE:BERRY Gangnam is an authorized provider with direct supply chain verification. Patients can inspect packaging before treatment.
35% of collagen injection patients at RE:BERRY Gangnam are male. Men typically seek temple volume restoration, jawline definition with Radiesse, and overall facial rejuvenation. The injection technique is adjusted for masculine facial proportions to maintain angular features while restoring volume.
Before: avoid blood-thinning medications (aspirin, ibuprofen) and supplements (fish oil, vitamin E, ginkgo) for 7 days to minimize bruising. After: no vigorous exercise for 24 hours, no facial massage except the prescribed Sculptra 5-5-5 protocol, avoid alcohol for 24 hours, and apply SPF 50+ daily.
1-2 days is sufficient for a single collagen injection session at RE:BERRY Gangnam. Same-day consultations and treatments are available. If a multi-session course is needed, sessions are spaced 4-6 weeks apart — many international patients schedule return visits or combine with other treatments during one trip.
Collagen injection restores volume but does not tighten lax skin. For sagging, RE:BERRY Gangnam recommends combining collagen injection with Sofwave (₩990,000/100 shots) or Ultherapy Prime for lifting. This combination addresses both volume loss and skin laxity without surgery.
40-60% cost savings compared to US, UK, and Australia for equivalent collagen injection procedures. Korea has the world’s highest concentration of aesthetic clinics per capita, driving competitive pricing. Sculptra at RE:BERRY Gangnam (₩590,000) compares to $800-$1,200 USD per vial in the United States.
Yes, diluted Sculptra is effective for neck crepiness and decolletage skin quality improvement. RE:BERRY Gangnam offers off-face collagen injection protocols for neck, hands, and decolletage. These areas typically require 1-2 sessions with results visible at 6-8 weeks post-treatment.
3 key differentiators: (1) all collagen injections are physician-performed with cannula technique for safety, (2) comprehensive collagen mapping with 3D volume assessment before treatment, (3) 14,000 sq ft facility with 30+ medical devices enabling combination protocols that maximize collagen injection results.
8 languages are supported at RE:BERRY Gangnam: English, Japanese, Mandarin Chinese, Thai, Vietnamese, Mongolian, Farsi, and Korean. Dedicated coordinators handle consultation interpretation, treatment explanation, aftercare instructions, and booking communication for collagen injection patients.
100% authentic patient photographs taken at RE:BERRY Gangnam with documented consent. All images are unretouched and captured during routine follow-up visits. Individual outcomes vary based on age, degree of volume loss, number of sessions, and skin type.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Ready to Restore Your Natural Collagen?
Book your collagen injection consultation with Dr. Yoon-Gon Ryu or Dr. Yejin Oh at RE:BERRY Gangnam — 2 minutes from Gangnam Station Exit 10. Same-day appointments available 365 days per year.
Book Your Collagen Injection Consultation
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- ✓ Free consultation with Dr. Yoon-Gon Ryu
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ Gangnam Station area, Seoul
- ✓ No downtime treatments available
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available