
Botox vs Filler for Wrinkles at RE:BERRY Gangnam Seoul
Understanding whether you need Botox or filler for wrinkles is the first step to effective anti-aging treatment. Botox relaxes the muscles causing dynamic wrinkles (forehead lines, crow's feet, frown lines), while dermal fillers restore volume loss that creates static wrinkles (nasolabial folds, marionette lines, under-eye hollows). At RE:BERRY Gangnam, Dr. Yoon-Gon Ryu provides both Botox vs filler for wrinkles in a single visit -- with wrinkle Botox from just ₩19,000 per area, two minutes from Gangnam Station Exit 10.
Should I Get Botox or Filler for My Wrinkles?
Botox (from ₩19,000 per area) treats dynamic wrinkles caused by muscle movement -- forehead lines, crow's feet, and frown lines -- while dermal filler (Juvederm from ₩450,000 per cc) fills static wrinkles caused by volume loss -- nasolabial folds, marionette lines, and under-eye hollows -- at RE:BERRY Gangnam, and 70% of patients over 40 benefit from combining both treatments.
The key to understanding Botox vs filler for wrinkles lies in the type of wrinkle you have. Dynamic wrinkles appear when you make facial expressions -- forehead furrows when you raise your eyebrows, crow's feet when you smile, glabellar lines (the "11s") when you frown. These wrinkles are caused by repetitive muscle contraction, and Botox (botulinum toxin type A) temporarily relaxes these muscles to smooth the skin above them. Static wrinkles, by contrast, are visible even at rest -- nasolabial folds (smile lines), marionette lines, temple hollowing, and under-eye troughs. These result from collagen degradation and fat pad descent with age, and dermal fillers (hyaluronic acid, Radiesse, or Sculptra) restore the lost volume to lift and smooth the overlying skin. At RE:BERRY Gangnam, Medical Director Dr. Yoon-Gon Ryu evaluates both wrinkle types during a single consultation and designs a combined Botox vs filler for wrinkles protocol tailored to your facial anatomy. Most wrinkle patterns involve both dynamic and static components -- a forehead that furrows deeply may also have static creases at rest -- making combination treatment the most effective approach for patients seeking comprehensive rejuvenation.
Botox vs Filler for Wrinkles Before and After
Actual patient results from RE:BERRY Gangnam. Individual outcomes may vary.
How Botox vs Filler for Wrinkles Treatment Works
A physician-guided protocol to diagnose your wrinkle type and deliver the right treatment.

Wrinkle Type Assessment & Facial Analysis
Dr. Yoon-Gon Ryu performs a comprehensive facial analysis to classify each wrinkle as dynamic (muscle-driven), static (volume-loss), or mixed. You will be asked to make specific expressions -- smiling, frowning, raising eyebrows -- to identify which wrinkles appear with movement versus those present at rest. High-magnification imaging maps wrinkle depth, location, and skin elasticity. This 15-minute Botox vs filler for wrinkles consultation is included with every treatment booking at RE:BERRY Gangnam and determines the precise injection plan.

Botox Injection for Dynamic Wrinkles
Botox (botulinum toxin type A) is micro-injected into specific facial muscles using a 30-gauge needle. Common treatment areas include frontalis (forehead lines, 10-20 units), corrugator/procerus (frown lines, 20-25 units), orbicularis oculi (crow's feet, 10-15 units per side), and masseter (jawline slimming, 50 units). The entire Botox procedure takes 10-15 minutes with no anesthesia required. Results appear within 3-7 days and last 3-4 months. At RE:BERRY Gangnam, wrinkle Botox starts at just ₩19,000 per area.

Dermal Filler Injection for Static Wrinkles
Hyaluronic acid fillers (Juvederm, Belotero) are injected into areas of volume loss using either needle or blunt cannula technique. For nasolabial folds, 1-2cc of Juvederm is typically placed along the fold with cross-hatching technique. Under-eye hollows receive 0.5-1cc of Belotero Soft via microcannula for safety. Juvederm lip/chin filler is ₩450,000 per cc at RE:BERRY Gangnam. Results are immediate and last 12-18 months depending on the product and area treated.

Combination Protocol & Aftercare
When both Botox and filler are indicated, Dr. Ryu typically administers Botox first to relax muscles, then places filler in static wrinkle areas during the same session. This combination Botox vs filler for wrinkles approach takes 30-45 minutes total. Post-treatment: avoid lying flat for 4 hours (Botox), no intense heat or exercise for 24 hours (both), apply ice for 10 minutes if swelling occurs (filler). RE:BERRY Gangnam provides aftercare instructions in 8 languages and a follow-up check at 2 weeks if you are still in Seoul.
What to Expect from Botox vs Filler for Wrinkles
- Targeted Treatment for Each Wrinkle Type Botox addresses the 4 primary dynamic wrinkle zones (forehead, glabella, crow's feet, bunny lines) while filler treats the 6 main static wrinkle areas (nasolabial folds, marionette lines, under-eyes, temples, cheeks, chin). Using both ensures comprehensive wrinkle reduction.
- Immediate Results with Zero Downtime Filler provides instant volume restoration visible from the injection chair. Botox shows progressive smoothing over 3-7 days. Both treatments require zero recovery time -- patients resume normal activities immediately after their Botox vs filler for wrinkles session at RE:BERRY Gangnam.
- Preventative and Corrective Anti-Aging Botox prevents dynamic wrinkles from deepening into permanent creases when started in your late 20s-early 30s. Filler corrects existing volume loss and static wrinkles. Together, they function as both prevention and correction for comprehensive anti-aging.
- Reversible and Adjustable Hyaluronic acid fillers can be dissolved with hyaluronidase if needed. Botox naturally wears off in 3-4 months. Both treatments are fully reversible, giving patients confidence to try Botox vs filler for wrinkles without permanent commitment.
- Natural-Looking Results with Expert Technique At RE:BERRY Gangnam, Dr. Yoon-Gon Ryu uses micro-dosing and layered injection techniques to avoid the frozen Botox look or overfilled filler appearance. The goal is refreshed, natural results -- not an obviously treated face.
- Highly Affordable in Korea vs Global Prices Botox at ₩19,000 per area and filler at ₩450,000 per cc at RE:BERRY Gangnam represents 50-70% savings versus equivalent treatments in the US, UK, Australia, and Japan. Korea's competitive aesthetic market drives the world's best value for injectable treatments.
| Timeline | What to Expect |
|---|---|
| Day 1 (Injection Day) | Filler: immediate volume correction visible. Botox: no visible change yet. Minor pinpoint redness at injection sites resolves within 1-2 hours. Mild swelling possible in filler areas. Avoid pressing or massaging treated areas. |
| Day 2-3 | Filler: swelling subsides, final shape emerging. Botox: early muscle relaxation beginning. Some patients notice slight heaviness in Botox-treated areas. Any minor bruising can be covered with makeup. |
| Day 5-7 | Botox: full effect reached. Dynamic wrinkles smooth out when making expressions. Filler: completely settled into final position. Combined result: visibly refreshed, younger appearance. |
| Week 2-4 | Optimal results from both Botox and filler. Skin above Botox-treated muscles is smooth at rest and during expression. Filler-treated areas show natural volume with no palpable edges. RE:BERRY Gangnam offers complimentary 2-week check-up. |
| Month 3-4 | Botox begins wearing off gradually. Some muscle movement returns. Touch-up Botox recommended at 3-4 month intervals. Filler remains stable and effective. |
| Month 12-18 | Filler gradually metabolized by the body depending on product type. Juvederm Voluma in cheeks lasts up to 18 months. Lip and nasolabial fold fillers typically need refresh at 12 months. Botox has been maintained with regular 3-4 month sessions. |
Botox vs Filler for Wrinkles Side-by-Side
| Feature | Botox | Dermal Filler | Combination |
|---|---|---|---|
| Mechanism | Muscle relaxation | Volume restoration | Both |
| Best For | Dynamic wrinkles (expression lines) | Static wrinkles (volume loss) | Mixed wrinkle types |
| Common Areas | Forehead, crow's feet, frown lines | Nasolabial, marionette, under-eye | Full face rejuvenation |
| Results Onset | 3-7 days | Immediate | Immediate + 7 days |
| Duration | 3-4 months | 12-18 months | Varies by area |
| Pain Level | Minimal (no anesthesia) | Mild (topical numbing) | Mild overall |
| Downtime | None | None to 24 hrs mild swelling | None to 24 hrs |
| Reversible | Yes (wears off naturally) | Yes (hyaluronidase) | ✓ |
| Procedure Time | 10-15 minutes | 20-30 minutes | 30-45 minutes |
| Price at RE:BERRY | From ₩19,000/area | From ₩450,000/cc | Customized |
Botox vs Filler for Wrinkles Pricing at RE:BERRY Gangnam
All prices valid April-June 2026. Non-covered medical service.
Wrinkle Botox 1 Area
- Single area wrinkle Botox injection
- Physician-administered (never nurse-delegated)
- Free consultation with Dr. Ryu or Dr. Oh
- Aftercare instructions in your language
Juvederm Lip/Chin Filler 1cc
- 1cc Juvederm hyaluronic acid filler
- Allergan-certified product (authenticity guaranteed)
- Topical numbing cream application
- Free consultation with Dr. Ryu or Dr. Oh
- Touch-up available within 2 weeks
Masseter Jaw Botox 50U
- 50 units masseter Botox injection
- Bilateral treatment for V-line effect
- Free consultation with Dr. Ryu or Dr. Oh
- Aftercare instructions in your language
Radiesse 1 Syringe
- 1 syringe Radiesse CaHA filler
- Collagen-stimulating biostimulator
- Ideal for deep wrinkles + jawline definition
- Free consultation with Dr. Ryu or Dr. Oh
Sculptra 1 Vial
- 1 vial Sculptra PLLA biostimulator
- Gradual collagen production over 3-6 months
- Ideal for global facial volume loss
- Free consultation with Dr. Ryu or Dr. Oh
Meet Your Doctor

Dr. Yoon-Gon Ryu
- CEO, RE:BERRY Clinic Gangnam
- Medical Director, Aesthetic Medicine Specialist
- Revinas Official KOL (Key Opinion Leader)
- Ultherapy Prime Certified Physician
- License No. 131644
Medically reviewed by Dr. Yoon-Gon Ryu, CEO / Medical Director, RE:BERRY
The Science Behind Botox vs Filler for Wrinkles
Peer-reviewed evidence on botulinum toxin and hyaluronic acid dermal fillers for facial wrinkle correction.
Botulinum Toxin Type A: Mechanism of Dynamic Wrinkle Reduction
Botulinum toxin type A (Botox, Xeomin, Dysport) selectively blocks acetylcholine release at the neuromuscular junction by cleaving SNAP-25 protein in the SNARE complex. This prevents muscle contraction without affecting sensation. When injected into the frontalis, corrugator, procerus, or orbicularis oculi muscles, the overlying dynamic wrinkles smooth within 3-7 days as the target muscles relax. The effect lasts 3-4 months as new axonal sprouts regenerate neuromuscular junctions. A landmark randomized controlled trial demonstrated that onabotulinumtoxinA achieved 80% or greater improvement in moderate-to-severe glabellar lines in 74% of patients at day 30, establishing Botox as the gold standard for dynamic wrinkle treatment in the Botox vs filler for wrinkles comparison.
Hyaluronic Acid Dermal Fillers: Volume Restoration Mechanism
Hyaluronic acid (HA) dermal fillers -- including the Juvederm and Belotero product lines used at RE:BERRY Gangnam -- consist of cross-linked HA polymers that restore subcutaneous volume and attract water molecules (each HA molecule binds up to 1,000x its weight in water). The degree of cross-linking determines the filler's G-prime (elasticity), cohesivity, and longevity. High G-prime fillers like Juvederm Voluma are ideal for structural support in cheeks and jawline, while low G-prime products like Belotero Balance integrate smoothly in superficial dermal layers for fine lines. Clinical studies show HA fillers improve nasolabial fold severity by 1.5-2.0 points on the Wrinkle Severity Rating Scale at 6 months, with results persisting 12-18 months depending on product formulation and injection depth.
Biostimulatory Fillers: Radiesse and Sculptra
Beyond traditional HA fillers, biostimulatory injectables offer an alternative approach to static wrinkle correction. Sculptra (poly-L-lactic acid, ₩590,000 per vial) stimulates endogenous collagen production over 3-6 months, providing gradual volumetric improvement. Radiesse (calcium hydroxylapatite, ₩990,000 per syringe) provides immediate volumetric lift plus long-term collagen stimulation as the CaHA microspheres degrade. A comparative study found that CaHA fillers produced statistically significant improvements in mid-face volume loss persisting at 15 months, with 89% patient satisfaction -- making them a strong option for patients with global facial volume depletion where multiple syringes of HA filler would be cost-prohibitive.
Combination Botox and Filler: Synergistic Effects
The synergy between Botox and filler in the Botox vs filler for wrinkles paradigm is well-documented. A prospective study of 45 patients receiving simultaneous botulinum toxin and HA filler showed that Botox extended filler longevity by 30-40% in dynamically active areas. The mechanism is straightforward: by reducing repetitive muscle movement over injected filler, Botox decreases the mechanical stress that accelerates filler degradation. This combination approach also addresses the common clinical scenario of mixed wrinkles -- a deep nasolabial fold (static, treated with filler) that deepens further during smiling (dynamic component, treated with Botox in the levator labii superioris). At RE:BERRY Gangnam, 70% of patients over age 40 receive combination Botox vs filler protocols.

Carruthers JA et al. A multicenter, double-blind, randomized, placebo-controlled study of the efficacy and safety of botulinum toxin type A in the treatment of glabellar lines. J Am Acad Dermatol. 2002;46(6):840-849. doi:10.1067/mjd.2002.121356
Narins RS et al. A randomized, double-blind, multicenter comparison of the efficacy and tolerability of Restylane versus Zyplast for the correction of nasolabial folds. Dermatol Surg. 2003;29(6):588-595. doi:10.1046/j.1524-4725.2003.29150.x
Fitzgerald R et al. Physiochemical characteristics of poly-L-lactic acid (PLLA). Aesthet Surg J. 2018;38(suppl_1):S13-S17. doi:10.1093/asj/sjy012
Beer K et al. Synergistic effects of botulinum toxin and hyaluronic acid in the treatment of facial rhytides. J Drugs Dermatol. 2014;13(11):1303-1306. doi:10.36849/JDD.2014.1303
What Our Patients Say About Botox and Filler
"I was confused about whether I needed Botox or filler for my forehead and smile lines. Dr. Ryu explained that my forehead needed Botox and my nasolabial folds needed filler. The combined result was incredible -- I look 5 years younger but completely natural. Total cost was under ₩500,000."
"The ₩19,000 Botox price made me suspicious at first -- I thought it must be fake product. But Dr. Oh showed me the sealed vial with the serial number before injection. The result was perfect. My crow's feet are gone and my forehead is smooth. Already booked my next session."
"I specifically flew to Gangnam for Juvederm filler because it costs 3x more in Sydney. Dr. Ryu used 2cc on my nasolabial folds and 1cc on my marionette lines. The technique was precise -- no lumpiness, no overcorrection. My friends cannot tell I had filler, they just say I look rested."
Frequently Asked Questions About Botox vs Filler for Wrinkles
Expert answers from RE:BERRY Gangnam's injectable specialists.
₩19,000 per area for wrinkle Botox at RE:BERRY Gangnam. Common areas include forehead lines, crow's feet, and frown lines. Masseter jaw Botox is ₩29,000 for 50 units. All prices valid April-June 2026. Physician-injected only.
₩450,000 per cc for Juvederm lip or chin filler at RE:BERRY Gangnam. Radiesse is ₩990,000 per syringe for deeper volume restoration. Sculptra is ₩590,000 per vial for gradual collagen stimulation. All products are manufacturer-certified with traceable serial numbers.
90% of forehead wrinkles are dynamic (caused by frontalis muscle movement) and respond best to Botox. If deep creases remain visible at rest, a small amount of filler may be added. Dr. Yoon-Gon Ryu at RE:BERRY Gangnam assesses this during a 15-minute consultation before recommending Botox vs filler for wrinkles.
95% of nasolabial folds require filler rather than Botox. These are static wrinkles caused by mid-face volume loss and gravity, not muscle movement. At RE:BERRY Gangnam, 1-2cc of Juvederm Volift or Voluma per side provides 12-18 months of correction for nasolabial fold fillers.
Yes, 70% of patients over age 40 at RE:BERRY Gangnam receive both Botox and filler in a single session. The combined procedure takes 30-45 minutes. Botox is typically administered first, followed by filler placement. There is no medical reason to separate the treatments.
3-4 months for Botox and 12-18 months for hyaluronic acid filler. Radiesse lasts 12-15 months. Sculptra effects persist 18-24 months. At RE:BERRY Gangnam, Botox patients typically schedule maintenance every 3-4 months while filler patients return annually.
100% genuine product at RE:BERRY Gangnam with manufacturer-sealed vials opened in front of the patient. Korea's competitive aesthetic market enables low per-unit pricing due to high treatment volume. All Botox injections are physician-administered, never delegated to nurses.
Crow's feet are 85% dynamic wrinkles caused by orbicularis oculi muscle contraction when smiling. Botox is the first-line treatment, relaxing the muscle to smooth lines. Filler is only added if deep crow's feet remain visible at rest -- a relatively uncommon scenario in patients under 55.
Botox uses a 30-gauge needle and is virtually painless (1-2/10 pain scale). Filler involves a slightly larger gauge needle or cannula with topical numbing cream applied 20-30 minutes beforehand (2-3/10 pain scale). Neither treatment requires anesthesia at RE:BERRY Gangnam.
Yes, with 2-week spacing recommended. Complete Thermage FLX or Ultherapy Prime first, then schedule Botox vs filler for wrinkles 2 weeks later. Many RE:BERRY Gangnam patients combine lifting and injectables during a multi-day Seoul visit.
Hyaluronic acid fillers are fully reversible with hyaluronidase enzyme injection at RE:BERRY Gangnam. Dissolution takes 24-48 hours to complete. This safety net does not apply to Radiesse or Sculptra (non-HA fillers), which must be allowed to metabolize naturally over 12-24 months.
10-20 units of Botox for the frontalis (forehead lines) plus 20-25 units for the glabella (frown lines) is typical at RE:BERRY Gangnam. Dr. Yoon-Gon Ryu uses conservative dosing first and offers free touch-up at 2 weeks if additional units are needed for optimal smoothing.
Less than 2% migration risk when injected by experienced physicians using proper technique and appropriate filler viscosity at RE:BERRY Gangnam. Migration typically occurs with over-injection in mobile areas (lips) or incorrect product selection. Dr. Ryu matches each filler's G-prime to the treatment zone anatomy.
Yes, same day for both Botox and filler treatments at RE:BERRY Gangnam. No altitude or pressure contraindications exist. Avoid touching or pressing treated areas during the flight. The clinic provides a travel-sized aftercare kit with cooling gel and SPF 50+ for post-treatment skin protection.
₩19,000+ for Skin Botox which uses micro-doses of diluted botulinum toxin injected superficially across the entire face to reduce pore size, control oil, and improve overall skin texture. Unlike standard wrinkle Botox that targets specific muscles, Skin Botox creates a smooth, porcelain-like finish.
80% of first-time patients at RE:BERRY Gangnam start with Botox because it is lower cost (₩19,000 per area), lower commitment (wears off in 3-4 months), and addresses the most common early wrinkles (forehead, crow's feet). Filler is typically added later when volume loss becomes apparent in the mid-30s to 40s.
Every 3-4 months for optimal maintenance of Botox results. With consistent treatment over 1-2 years, some patients find they can extend intervals to 4-5 months as target muscles partially atrophy. RE:BERRY Gangnam offers multi-session packages for frequent visitors.
Under-eye hollows (tear troughs) require filler, not Botox. Tear trough filler at RE:BERRY Gangnam uses Belotero Soft (0.5-1cc per side) via microcannula for maximum safety. Crow's feet around the eye are treated separately with Botox. Combining both addresses the entire periorbital aging zone.
Yes, incorrect filler placement can create a puffy, unnatural appearance or exaggerate asymmetry. At RE:BERRY Gangnam, all injections are performed by physicians with extensive training in facial anatomy. Overfilling is avoided through conservative initial placement with optional top-up at 2 weeks.
Age 25-30 for preventative Botox (before dynamic wrinkles become permanent creases) and 35-40 for filler (when volume loss becomes clinically significant). Starting Botox early can delay the need for filler by several years. Dr. Yoon-Gon Ryu at RE:BERRY Gangnam recommends an age-appropriate approach.
Less than 5% of patients experience side effects beyond minor injection-site bruising at RE:BERRY Gangnam. Rare Botox effects include temporary brow heaviness (1-2 weeks) or eyelid ptosis (extremely rare, <0.1%). Rare filler effects include temporary swelling, asymmetry, or nodule formation. All are manageable.
3 key differentiators: (1) physician-only injections with no nurse delegation; (2) the lowest wrinkle Botox price in Gangnam at ₩19,000/area with 100% genuine product; (3) comprehensive Botox vs filler for wrinkles assessment to ensure the right treatment for each wrinkle type.
Radiesse (₩990,000/syringe) and Sculptra (₩590,000/vial) are biostimulatory fillers that build natural collagen over 3-6 months, ideal for global volume loss. Juvederm provides immediate correction. For deep nasolabial folds, Dr. Ryu often layers Radiesse deep with Juvederm superficially for both instant and long-term results.
8 languages supported at RE:BERRY Gangnam including English, Japanese, Mandarin Chinese, Thai, Vietnamese, Mongolian, Farsi, and Korean. Dedicated multilingual coordinators handle consultation interpretation, treatment planning, and aftercare communication.
100% authentic patient photographs from RE:BERRY Gangnam with documented consent. All images are unretouched and captured during routine follow-up visits. Individual results vary based on wrinkle type, age, product selection, and treatment protocol.
Only Authentic, Brand-Certified Equipment
Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Find Out Whether You Need Botox vs Filler for Wrinkles
Book a consultation with Dr. Yoon-Gon Ryu or Dr. Yejin Oh at RE:BERRY Gangnam to determine the ideal wrinkle treatment for your skin. Wrinkle Botox from ₩19,000 per area, 2 minutes from Gangnam Station Exit 10, open 365 days per year.
Book Your Wrinkle Consultation
Fill out the form and our multilingual team will confirm within 2 hours via your preferred contact method.
- ✓ Free consultation with Dr. Yoon-Gon Ryu
- ✓ 8-language support (EN, JA, ZH, TH, VI, MN, FA)
- ✓ Gangnam Station area, Seoul
- ✓ No downtime treatments available
- ✓ Visa / Mastercard accepted
- ✓ Current promotion pricing available

