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Smile Line Filler Duration

How Long Do Smile Line Fillers Last in Gangnam, Seoul

From โ‚ฉ200,000 (about $143)

How long a smile line filler lasts is set by three readable things: which gel goes in, how deep it sits away from the moving crease, and how fast your own body clears it. The nasolabial fold is a high-motion zone, so RE:BERRY reads all three before injecting, steps from Gangnam Station in Seoul.

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Smile Line Filler Duration

Smile Line Filler

Smile Line Filler Duration ยท Gangnam Seoul

From โ‚ฉ200,000 (about $143)

How long a smile line filler lasts is set by three readable things: which gel goes in, how deep it sits away from the moving crease, and how fast your own body clears it. The nasolabial fold is a high-motion zone, so RE:BERRY reads all three before injecting, steps from Gangnam Station in Seoul.

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Quick Answer

How long do smile line fillers actually last?

A smile line filler lasts about 9 to 15 months for a hyaluronic-acid gel, 12 to 18 months for a calcium-hydroxylapatite gel, and 18 to 24 months for poly-L-lactic acid. The nasolabial fold is a high-movement zone; the muscles around the mouth pull on it during nearly every expression, so the gel breaks down faster there than in a still region, and how deep the physician places it swings the answer by months. At RE:BERRY Gangnam the treating physician reads fold depth, movement, and your own clearance rate before naming the window you should expect.

Effects & Progress

Effects & Progress

The softening shows the day the gel is placed, but the real question is how long it holds โ€” a well-planned smile line fades slowly and evenly, never dropping off a cliff.

TimelineWhat to Expect
Right after

The smile-line shadow looks softer immediately, though swelling can make the fold read fuller than the plan; small marks fade within an hour or two and light makeup and travel are fine the same day. Duration is not judged yet.

After 2 weeks

Most swelling has gone and the fold starts to read true. The gel has integrated into the tissue, no longer a distinct lump, and this is the volume that will actually age down over the coming months.

After 1โ€“3 months

The settled softening is visible at the two-week review against the day-zero photos. How much correction your own fold kept here is the reading that sets your personal refresh interval. Response speed varies by individual.

6โ€“12 months

Maintenance period. A hyaluronic-acid smile line commonly holds around 9 to 15 months, longer for calcium-based and poly-L-lactic acid gels; because it is HA, the result can be adjusted or dissolved at any point, and RE:BERRY guides the top-up timing from how your own fold held.

Treatment Process

Smile Line Filler Duration Planned from Product, Depth, and Fold Movement

โ€ป Illustrative images are AI-generated to help explain the treatment process.
STEP 1

STEP 1. 1:1 Personal Consultation

Your physician lifts the cheek and watches the fold move, judging how much is a true crease versus a dropped-cheek shadow, then names the hold window each candidate gel would give in a zone this active.

STEP 2

STEP 2. Cleansing & Numbing Cream

After cleansing, numbing cream rests for 20โ€“30 minutes. The sealed product label is confirmed with you before opening.

STEP 3

STEP 3. Precision Dermal Injection

The gel is laid deep on the low-movement plane through a blunt cannula, the depth that both supports the fold and holds longest, with only a light surface feather where blending is needed. Deep placement is a duration choice, not just a shape one.

STEP 4

STEP 4. Soothing Care & Aftercare Guide

Cold compresses follow and daily life resumes the same day. The fold reads softer at once and settles true around two weeks; that review sets your personal refresh clock, and a light 8-month top-up keeps the result continuous.

Effects & Progress

Effects & Progress

Fades Slowly, Not All at Once

The immediate result is the easy part: gel placed along the fold eases the shadow as soon as it is in. What separates a durable plan is how that softening leaves. Hyaluronic acid is broken down by the body a little at a time, so a smile line planned well loses its correction gradually and evenly across its months, and most people notice a slow return of the shadow long before the fold is truly back. That gentle fade is why the honest measure of a smile line filler sits around month ten, not on the day it went in.

Fine Lines & Pores

Longevity is written into the material before it reaches the fold. A cross-linked hyaluronic acid gel generally holds around 9 to 15 months in the smile line; a calcium-hydroxylapatite gel works partly by prompting your own collagen and tends to run 12 to 18; a poly-L-lactic acid product builds collagen slowly over months and can reach 18 to 24. Cross-linking density and cohesivity decide how fast a gel is cleared, so the physician selects to the duration you want as much as to the softening. The same fold can therefore be given a shorter, fully reversible plan or a longer structural one.

Texture & Glow

Duration and control usually pull against each other, and hyaluronic acid is where they meet. Because an enzyme called hyaluronidase, kept on-site, dissolves HA, a result that reads too full or uneven can be corrected the same day, with no year-long wait. That reversibility is why many guests choosing a longer-lasting plan still start with HA: they get months of hold without giving up the ability to change their mind, and it doubles as the safety lever in the rare event of a vessel concern in a region crossed by named arteries.

Depth and Care Move the Clock

The plan does not end at the syringe. Gel placed deep on the still plane is cleared more slowly than the same gel placed shallow in tissue that flexes all day, and in the smile line that gap is documented near 23 percent longer than subcutaneous placement. Everyday habits nudge it further: strong sun and repeated heat speed the breakdown of hyaluronic acid, so daily sun protection and easing off saunas early in the settling period genuinely stretch the result. None of this is about doing more filler; it is about the placed volume lasting the way it was meant to.

Timeline
What to Expect
Right after
The smile-line shadow looks softer immediately, though swelling can make the fold read fuller than the plan; small marks fade within an hour or two and light makeup and travel are fine the same day. Duration is not judged yet.
After 2 weeks
Most swelling has gone and the fold starts to read true. The gel has integrated into the tissue, no longer a distinct lump, and this is the volume that will actually age down over the coming months.
After 1โ€“3 months
The settled softening is visible at the two-week review against the day-zero photos. How much correction your own fold kept here is the reading that sets your personal refresh interval. Response speed varies by individual.
6โ€“12 months
Maintenance period. A hyaluronic-acid smile line commonly holds around 9 to 15 months, longer for calcium-based and poly-L-lactic acid gels; because it is HA, the result can be adjusted or dissolved at any point, and RE:BERRY guides the top-up timing from how your own fold held.

Treatment Process

Smile Line Filler Duration Planned from Product, Depth, and Fold Movement

โ€ป Illustrative images are AI-generated to help explain the treatment process.
STEP 1. 1:1 Personal Consultation
STEP 1. 1:1 Personal Consultation

The visit opens with a plainer question than most people expect: not only how you want the smile line softened, but how long you want it to stay. Your physician lifts the cheek with a finger and watches the fold move, because a nasolabial line that vanishes when the cheek is raised is a descended cheek, not a crease, and each cause holds gel for a different length of time. Skin thickness, how much the fold flexes when you talk, and your general clearance rate are all noted, since a mobile fold ages a filler faster than a still region. The gel and its expected window are agreed before anything is opened, not after.

STEP 2. Cleansing & Numbing Cream
STEP 2. Cleansing & Numbing Cream

A numbing option settles while the physician confirms the exact product chosen for the hold window you agreed. The syringe is unsealed where you can watch it, and its lot number is read against the MFDS registry, so the genuine gel on your plan is verifiably the one that goes in. Treatment points are marked toward the deeper plane, away from the surface of the crease, because that is where clearance runs slowest and the duration you were quoted is earned.

STEP 3. Precision Dermal Injection
STEP 3. Precision Dermal Injection

Working away from the busiest part of the crease, the physician lays the structural volume on the deep supraperiosteal plane through a blunt cannula, then feathers only a small amount nearer the surface. Depth is deliberate for a reason beyond shape: gel on the low-movement plane is cleared more slowly than gel sitting shallow in tissue that flexes with every word, so the deep placement buys retention as well as support. The cannula also keeps bruising and vessel risk low across a fold crossed by named arteries. Volume is built gradually and checked with you upright, since the face you are seen in stands up while the table has you lying flat.

STEP 4. Soothing Care & Aftercare Guide
STEP 4. Soothing Care & Aftercare Guide

A cooling pack and regeneration cream soothe the skin right after treatment. Embossing and mild bruising may last 2โ€“5 days; avoid sauna, alcohol, and intense exercise on the day. We recommend 3 sessions at 3โ€“4 week intervals, then maintenance every 6โ€“12 months.

Benefits & Results

What Sets Smile Line Filler Duration โ€” and How the Result Fades

  • Product decides the baseline: cross-linked hyaluronic acid in the smile line commonly holds 9 to 15 months, a calcium-hydroxylapatite gel 12 to 18, and poly-L-lactic acid 18 to 24 as its collagen-building effect runs on after the gel is gone
  • The nasolabial fold is a high-motion zone; the muscles around the mouth load it with roughly three times the mechanical stress of a still facial region, which is the single biggest reason smile line gel fades faster than gel elsewhere
  • Depth adds months: gel placed supraperiosteally on the deep plane sits in tissue that barely moves and clears measurably slower than the same gel placed shallow, an edge documented at around a 23% longer duration than subcutaneous placement
  • A planned mid-course top-up stretches the effective result far past a single session: refreshing roughly 30 to 40% of the volume around the 8-month mark can carry the smile line well beyond 30 months of continuous correction
  • Because it is hyaluronic acid, the result is not locked in: an enzyme called hyaluronidase can adjust or dissolve the gel, so a longer plan never means being stuck with a shape you dislike
  • The same physician reads your fold, places the gel, and reviews the settle, so your smile line case in Gangnam is never handed to another practitioner between the plan and the top-up
TimelineWhat to Expect
The fold reads softer the moment the gel is placed, though early swelling can make it look slightly fuller than it will hold; light makeup and travel are fine the same day
Swelling clears and the gel integrates, so the true settled softening surfaces: the reading the physician uses to set your personal refresh interval
Most people notice a slow, even softening of the correction well before it is gone; an 8-month light top-up here keeps the result continuous, so nothing restarts from zero
The window closes at a pace set by the product and your own clearance: HA nearer the front of the range, calcium-based and poly-L-lactic acid gels holding longer
Comparison

Smile Line Filler Duration by Product โ€” HA vs Calcium-Based vs Poly-L-Lactic Acid

CriteriaHyaluronic Acid (RE:BERRY Gangnam)Calcium HydroxylapatitePoly-L-Lactic Acid
How it worksCross-linked HA gel adds volume directly and draws water into the tissueCalcium microspheres in a gel add volume and prompt some of your own collagenStimulates gradual collagen build over months; the carrier resorbs early
Typical smile line holdAbout 9 to 15 monthsAbout 12 to 18 monthsAbout 18 to 24 months
Result timingVisible immediately, settles true by around two weeksImmediate volume, with collagen effect layering inBuilds slowly across several months, not instant
ReversibleYes; hyaluronidase can adjust or dissolve itNot enzyme-reversibleNot enzyme-reversible
Best suited toFirst-timers and anyone wanting an adjustable, reversible smile lineDeeper folds wanting firmer, longer structural supportGradual, longer-term correction across the midface and fold
Top-up rhythmLight refresh around 8 months keeps it continuousLonger interval between sessionsLongest interval; assessed once collagen has built

Why This Matters

The reason a smile line filler runs shorter than a cheek or temple filler is mechanical. The zygomaticus major and the muscles around the mouth pull on the nasolabial fold through nearly every expression (talking, chewing, laughing), loading it with roughly three times the movement of a still region. Gel in a busy zone is broken down faster, so the physician at RE:BERRY Gangnam plans depth and product around that motion, never around a single average.

Where the gel sits matters as much as which gel it is. Placed supraperiosteally, on the deep plane where the tissue barely moves, hyaluronic acid is cleared more slowly than the same gel placed shallow in flexing tissue; the deep zone shows lower enzyme activity and the documented duration edge lands near 23%. This is why deep, low-movement placement is treated as a longevity choice, not only a shaping one, and why a blunt cannula is used to reach that plane while keeping bruising and vessel risk low.

KHIDI's 2025 international patient survey found 41.4% of respondents rank keeping the same doctor throughout as their leading criterion. At RE:BERRY the physician who reads your fold and names the duration window is the one who places the gel and reviews the settle, so the top-up timing is judged against your own record rather than a generic calendar.

Sources: KHIDI 2025 Medical Tourism Survey; manufacturer device and product specifications; peer-reviewed filler duration literature; RE:BERRY clinic records (verified).
Best for: Wants the smile line softened but values being able to adjust or dissolve the result, and is fine with a top-up
Hyaluronic acid (reversible)
HA holds around 9 to 15 months in the fold and can be corrected the same day with hyaluronidase, so a longer plan never traps you
Best for: Deeper, static fold wanting the longest interval between sessions and comfortable with a non-reversible gel
Poly-L-lactic acid or calcium-based
Collagen-building and calcium gels commonly run 12 to 24 months, trading enzyme reversibility for a longer hold
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Pricing

Smile Line Filler Sessions in Gangnam (Regular Rates, VAT Included)

Consultation-based, quoted at your free consultation
From โ‚ฉ200,000 (about $143)
Get Your Personalized Quote
Your Doctors

Your Medical Director

Dr. Yoon-Gon Ryu

Dr. Yoon-Gon Ryu

CEO / Medical Director
"People ask me for a number, but a smile line moves through nearly every word you say, so I would rather tell you the truth: the gel I place deep on the still plane outlasts the one packed into the moving crease, and at your two-week review I will set your top-up clock from how your own fold held โ€” not from an average on a chart."
  • Medical Director, RE:BERRY Aesthetic Clinic Gangnam โ€” Korean MOHW Medical License No.131644
  • Manufacturer-appointed KOL invited to teach injection and energy-device technique to Korean peers
  • Regular Member, Korean Academy of Aesthetic Medicine
  • Co-manages every case with Dr. Yejin Oh (Korean MOHW Medical License No.144238)
  • Featured in Authority Magazine (2026)
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Medically reviewed by Dr. Yoon-Gon Ryu, CEO / Medical Director, RE:BERRY

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Step past the black gallery facade and the bustle of Gangnam-daero falls away. Fourteen thousand square feet of hushed corridors, marble installations, a cascading water feature and fully enclosed consultation suites โ€” arranged so you rarely cross paths with another guest, because our reservation-only diary keeps every hour deliberately underbooked.

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Clinical Science

The Evidence Behind How Long a Smile Line Filler Holds

How long a hyaluronic-acid filler lasts in the nasolabial fold is written into the material before it reaches your face. The physical properties of an HA gel (its cross-linking density, elastic modulus, and cohesivity) govern how quickly the body clears it, and comparative rheology work across gel categories showed that firmer, more elastic gels resist deformation and degradation differently in mobile regions than softer ones. Matching a product to the movement of the smile line, then, is the starting point for a durable result; a single default syringe leaves the retention to chance.

Sundaram H, Voigts B, Beer K, Meland M. Comparison of the rheological properties of viscosity and elasticity in two categories of soft tissue fillers: gel-particle and cohesive polydensified matrix. Dermatol Surg. 2010;36 Suppl 3:1859-1865. doi:10.1111/j.1524-4725.2010.01743.x

Multicenter trial data anchor the working duration figures. A randomized comparison of non-animal stabilized hyaluronic acid in the nasolabial fold recorded correction that was maintained at review points across the months following treatment, supporting the roughly 9-to-15-month range quoted for HA in this high-movement zone; calcium-hydroxylapatite gels, which add volume while prompting some of the patient's own collagen, ran longer in head-to-head comparison. These findings track what the physician at RE:BERRY Gangnam explains at consultation: the product sets the baseline window, and the mobile fold shortens it relative to a still region.

Narins RS, Brandt F, Leyden J, Lorenc ZP, Rubin M, Smith S. A randomized, double-blind, multicenter comparison of the efficacy and tolerability of Restylane versus Zyplast for the correction of nasolabial folds. Dermatol Surg. 2003;29(6):588-595. doi:10.1046/j.1524-4725.2003.29150.x

Moers-Carpi MM, Tufet JO. A multicenter, randomized trial comparing calcium hydroxylapatite to two hyaluronic acids for treatment of nasolabial folds. Dermatol Surg. 2007;33 Suppl 2:S144-S151. doi:10.1111/j.1524-4725.2007.33354.x

Safety runs alongside longevity in a fold crossed by named vessels. Global consensus work on hyaluronic-acid injection stresses slow delivery of small aliquots and vascular awareness, and the availability of hyaluronidase as an on-site reversal agent is part of why many guests choosing a longer-lasting plan still begin with HA. A blunt cannula reaching the deep supraperiosteal plane both lowers vessel risk and places the gel where clearance is slowest โ€” the practical reason depth is discussed as a duration lever, not only a shaping one, at RE:BERRY Gangnam.

Signorini M, Liew S, Sundaram H, et al. Global Aesthetics Consensus: avoidance and management of complications from hyaluronic acid fillers-evidence- and opinion-based review and consensus recommendations. Plast Reconstr Surg. 2016;137(6):961e-971e. doi:10.1097/PRS.0000000000002184

Common Questions

Questions International Guests Ask About Smile Line Filler Duration

How long do smile line fillers actually last?

It depends on the gel and where it is placed. A hyaluronic-acid smile line filler generally holds around 9 to 15 months, a calcium-hydroxylapatite gel 12 to 18 months, and poly-L-lactic acid 18 to 24 months. The nasolabial fold moves constantly, so the same gel fades faster there than in a still part of the face, and the physician at RE:BERRY Gangnam names the window that fits your fold at consultation.

Why does filler in the smile line fade faster than filler elsewhere?

The muscles around the mouth and cheek pull on the nasolabial fold during nearly every expression (talking, chewing, smiling), loading it with roughly three times the mechanical stress of a static region. Gel in a busy zone is broken down more quickly, which is the main reason a smile line result runs shorter than, say, a temple or forehead filler placed in still tissue.

Which smile line filler lasts the longest?

Among the common options, poly-L-lactic acid tends to run longest at roughly 18 to 24 months because it works by building your own collagen over time, followed by calcium-hydroxylapatite gels at 12 to 18 months. Hyaluronic acid sits at 9 to 15 months but earns its place by being adjustable and reversible, so the longest-lasting choice is not automatically the right one for every face.

Does injection depth really change how long the filler holds?

Yes, noticeably. Gel placed deep on the supraperiosteal plane sits in tissue that barely moves and shows lower clearance activity, so it is broken down more slowly than the same gel placed shallow in flexing tissue โ€” the documented edge lands near 23% longer duration. That is why the physician at RE:BERRY Gangnam treats depth as a longevity decision and uses a blunt cannula to reach that plane.

Can I make my smile line filler last longer with aftercare?

Aftercare will not double the result, but it protects it. Strong sun and repeated heat speed the breakdown of hyaluronic acid, so daily sun protection and easing off saunas and hot yoga early in the settling period genuinely help. For the first few days, avoid firm pressure and intense heat on the area; beyond that, ordinary habits are what keep the gel lasting the way it was planned to.

When should I get a top-up for my smile line?

Rather than waiting for the correction to disappear, many guests refresh roughly 30 to 40% of the volume around the 8-month mark. Topping up while some gel remains keeps the smile line continuously corrected and can carry the effective result well past 30 months. At RE:BERRY Gangnam the timing is set from your two-week review reading and how your own fold has held since.

What are the signs it is time to redo my smile line filler?

The usual sign is a slow, even return of the shadow along the fold: makeup starting to settle into the line again, or the crease reading deeper in photos than it did a few months earlier. Because HA fades gradually, without any sudden drop-off, most people notice this softening return well before the filler is fully gone, which is the ideal moment for a light top-up.

Are smile line fillers reversible if I do not like the result?

Hyaluronic-acid smile line fillers are. An enzyme called hyaluronidase, kept on-site, can dissolve or adjust the gel, so a result that looks too full or uneven can be corrected without waiting out the full duration. Calcium-based and poly-L-lactic acid gels are not enzyme-reversible, which is one reason many first-time guests start with HA even when they want a longer plan.

Does hyaluronidase work at any time after injection?

Hyaluronidase dissolves hyaluronic-acid gel most predictably in the early window after treatment โ€” within about 72 hours it is essentially fully reversible โ€” and it still works later, though a settled, integrated gel may need more of the enzyme or a repeat pass. It is also the reason HA is favoured in a fold crossed by named arteries, since it doubles as the reversal lever in the rare event of a vessel concern.

Will my smile line get worse or look 'deflated' when the filler wears off?

No. When a hyaluronic-acid filler is cleared, the fold simply returns toward how it looked before treatment โ€” the gel does not stretch or damage the tissue on its way out. Poly-L-lactic acid is a little different in that it leaves some of your own collagen behind, so the fade can be softer, but nothing about a well-placed filler leaves the smile line worse than its starting point.

Is longer-lasting filler always the better choice for smile lines?

Not for everyone. A longer hold means a longer wait if you dislike the shape, so first-time guests and anyone unsure of the look they want often do better with reversible HA. A firmer, longer-lasting gel suits a deeper, more static fold in someone who already knows the result they like. The physician at RE:BERRY Gangnam matches the trade-off to your fold and your goals rather than defaulting to the longest option.

How does the physician confirm the exact product going into my smile line?

Every syringe is unsealed in front of you, and its lot number is checked against the MFDS registry before anything is placed, so the product on your plan is verifiably the one that goes in. This matters for duration too โ€” the hold you were quoted assumes a specific genuine gel, and lot-number verification is how RE:BERRY Gangnam keeps that promise honest.

Can I get smile line filler done in one Seoul visit as a traveler?

Yes. Consultation, the fold reading, and placement fit into a single appointment, and because there is no wound, light makeup and travel are fine the same day. Message RE:BERRY on WhatsApp with your dates โ€” a coordinator replies in English, interpreters cover 8 languages on-site, and the clinic is a 2-minute walk from Gangnam Station Exit 10, so it slots between sightseeing easily.

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Only Authentic, Brand-Certified Equipment

Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.

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Ask How Long Your Smile Line Filler Would Last in Gangnam

Send your fold photos and how long you want the result to hold to RE:BERRY on WhatsApp โ€” a coordinator replies in English, and the physician who reads your fold names the duration window and places the gel. Nothing is scheduled until you confirm, and the smile line settles enough to travel the same day.

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i had a good time having the Juvelook treatment!
It was my first time in Korea, all the Doctor & team are bery helpful. Dr. Ian & cheong a lee(jenny) are really helpful.

I understand more about my skin.

The clinic is calm, welcoming.

there are many activities i didnโ€™t expect to find in a beauty clinic; phot...

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When you walk into the clinic, it genuinely feels like a luxury experience.
The staff was so kind and attentive the whole time ๐Ÿค.
The consultation felt very personalized, and they recommended treatments that truly matched what my skin needed instead of just recommending anything.
Honestly, I hope to come back next year

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Great place! Came coz of an ad online and wanted to check out the place. They were able to fit me and my husband in right away as walk-ins. They took us to a sink to wash our faces, then took photos for skin analysis and before photos. Then they proceeded to give us a consultation ( c/o Jin Wooyoung) and advice on what...

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So happy to found the beauty clinic in Korea that very inclusive and Muslim friendly. They have a prayer space for muslim and they prepare a female doctor for me. The clinic is so comfortable with aesthetic design make me feel relaxed. The doctor and the staff are very professional and helpful so all of the procedure r...

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I had an excellent experience at Reberry Gangnam. The staff were professional, welcoming, and took the time to explain each treatment thoroughly. I had microneedling and other skin treatments, and the entire process was comfortable and well-organized. The clinic was modern, clean, and made me feel at ease from start to...

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SCIENTIFIC EVIDENCE

Science Smile line filler duration โ€” peer-reviewed references

The duration of a hyaluronic-acid filler in the nasolabial fold rests on both the material and the placement. Comparative rheology across filler categories (Sundaram 2010) showed that a gel's elasticity and cohesivity govern how it behaves and degrades in mobile tissue, so product choice sets the baseline window. Multicenter trial evidence anchors the working figures: a randomized nasolabial-fold comparison of stabilized hyaluronic acid documented maintained correction across follow-up (Narins 2003), and a head-to-head trial found calcium-hydroxylapatite outlasting hyaluronic acid in the same fold (Moers-Carpi 2007). Global consensus guidance (Signorini 2016) frames the slow-aliquot, vessel-aware, hyaluronidase-backed technique that lets a longer plan stay reversible. Together these sources support the ranges quoted here โ€” roughly 9 to 15 months for HA, 12 to 18 for calcium-based gels, 18 to 24 for poly-L-lactic acid โ€” and the point that a high-movement fold shortens them relative to still regions.

  • Sundaram H, Voigts B, Beer K, Meland M. Comparison of the rheological properties of viscosity and elasticity in two categories of soft tissue fillers: gel-particle and cohesive polydensified matrix. Dermatol Surg. 2010;36 Suppl 3:1859-1865. doi:10.1111/j.1524-4725.2010.01743.x
  • Narins RS, Brandt F, Leyden J, Lorenc ZP, Rubin M, Smith S. A randomized, double-blind, multicenter comparison of the efficacy and tolerability of Restylane versus Zyplast for the correction of nasolabial folds. Dermatol Surg. 2003;29(6):588-595. doi:10.1046/j.1524-4725.2003.29150.x
  • Moers-Carpi MM, Tufet JO. A multicenter, randomized trial comparing calcium hydroxylapatite to two hyaluronic acids for treatment of nasolabial folds. Dermatol Surg. 2007;33 Suppl 2:S144-S151. doi:10.1111/j.1524-4725.2007.33354.x
  • Signorini M, Liew S, Sundaram H, et al. Global Aesthetics Consensus: avoidance and management of complications from hyaluronic acid fillers-evidence- and opinion-based review and consensus recommendations. Plast Reconstr Surg. 2016;137(6):961e-971e. doi:10.1097/PRS.0000000000002184

These references shape how smile line filler duration is planned at RE:BERRY's Gangnam aesthetic clinic: product selected to the retention window agreed with you; supraperiosteal, blunt-cannula placement on the low-movement plane where clearance runs slowest; genuine gel confirmed by lot-number verification; and a two-week settle review that sets your personal refresh interval from your own fold, never from an average. This information is for educational purposes only and is not medical advice.

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RE:BERRY Clinic Gangnam

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