
Palm Hyperhidrosis Botox in Gangnam -- 100U Grid Pattern, Lasts 6-9 Months
Palmar hyperhidrosis (excessive sweaty palms) affects 1-3% of adults and can disrupt handshakes, paperwork, and touchscreen use. At RE:BERRY Clinic Gangnam, Dr. Yoon-Gon Ryu (License 131644) treats palmar sweating with 100 units of botulinum toxin per palm using a grid injection pattern at 1-1.5cm intervals -- effect typically lasts 6-9 months.
How Much Is Palm Hyperhidrosis Botox at RE:BERRY Gangnam?
Palm hyperhidrosis Botox (100U per palm). Dr. Yoon-Gon Ryu (Lic.131644) performs at RE:BERRY Gangnam (Gangnam Station Exit 10, 2 min walk). KHIDI M-2025-01-08-09203.
Palmar hyperhidrosis is treated at RE:BERRY Gangnam with 100 units of botulinum toxin per palm administered in a grid injection pattern (1-1.5cm spacing, typically 25-30 injection points per palm), with effect lasting 6-9 months — meaningfully longer than the 4-6 months reported for axillary treatment. Dr. Yoon-Gon Ryu (License 131644), CEO and Medical Director, personally performs every palmar injection. The clinic is 2 minutes walk from Gangnam Station Exit 10 (Line 2). For patients combining this with botox and fillers or underarm hyperhidrosis, the consultation fee is bundled. KHIDI-registered as international patient attraction clinic (M-2025-01-08-09203).
How Palm Hyperhidrosis Botox Works at RE:BERRY Gangnam
Five-step protocol Dr. Yoon-Gon Ryu uses for grid-pattern palmar botulinum toxin injection.

Hyperhidrosis Severity Assessment & Minor's Starch-Iodine Test
Dr. Yoon-Gon Ryu uses the Hyperhidrosis Disease Severity Scale (HDSS) to confirm primary palmar hyperhidrosis (HDSS ≥3). Minor's iodine-starch test is then performed: iodine solution is painted on each palm, dried, then dusted with potato starch. Sweat zones turn deep purple-black within 5-10 minutes, mapping active eccrine gland density. This visualization ensures every grid point lands on a sweating gland rather than following a generic template, improving efficacy by 15-25%.

Topical EMLA + Optional Ice Pre-Cooling
Palms contain 3x more nerve endings than underarms, so topical lidocaine-prilocaine (EMLA 5%) is applied under occlusive dressing for 30 minutes. Ice pre-cooling is offered for 5 minutes immediately before injection to further reduce sensation. With this combined protocol, average reported pain is 3-4/10 VAS even with 25-30 injection points per palm.

Grid Pattern Mapping (1-1.5cm Spacing)
A surgical marker is used to draw a grid across the active sweat zone identified by Minor's test, with intersections spaced 1-1.5cm apart. The standard palm receives 25-30 grid points covering the central palm and the four finger pads. This spacing is the published reference for palmar treatment (Park 2019, PMID:31197861) and ensures diffusion zones from each 2-3 unit micro-injection overlap to silence the eccrine field uniformly.

100U Intradermal Injection per Palm (32G Needle)
Dr. Ryu injects 2-3 units of botulinum toxin per grid point at 2-3mm intradermal depth using a 32G ultra-fine needle. The total of 100 units per palm is the dose validated by FDA-cleared protocols and Korean cohort data. The intradermal plane is critical: deeper intramuscular injection risks transient thenar/hypothenar weakness, so depth control is the most operator-dependent step (Lee 2021, PMID:34227190). Bilateral treatment takes 15-20 minutes total.

Post-Procedure Care & 2-Week Follow-Up
Zero downtime: patients can drive and use phones immediately. Avoid intense gripping activities, hand massages, and saunas for 24 hours. Dryness onset begins day 3-5, with peak 80-90% sweat reduction at day 14. A WhatsApp follow-up at week 2 confirms result; touch-up at 50% price is available if any isolated wet patches remain (typical touch-up rate <8% at RE:BERRY Gangnam).
What to Expect from Palm Hyperhidrosis Botox at RE:BERRY Gangnam
- 80-90% Palmar Sweat Reduction: Gravimetric studies demonstrate average sweat reduction of 80-90% on the palms after 100U dosing in the grid pattern Dr. Ryu uses (Carruthers 2007, PMID:18086050).
- 6-9 Month Duration: Palmar effect lasts longer than axillary because palmar eccrine glands have slower acetylcholine receptor turnover -- typical re-treatment interval at RE:BERRY Gangnam is 7-8 months.
- Confidence in Handshakes & Documents: Dermatology Life Quality Index (DLQI) improvement averages 70-80% after palmar treatment, restoring confidence in handshakes, paperwork, and touchscreen use.
- No Surgical Risk: Unlike endoscopic thoracic sympathectomy (ETS surgery), botulinum toxin causes zero compensatory sweating, no Horner's syndrome, and is fully reversible (effect simply wears off).
- KHIDI-Registered International Care: RE:BERRY Gangnam holds KHIDI M-2025-01-08-09203 international patient attraction registration, with 8-language consultation support.
| Timeline | What to Expect |
|---|---|
| Day 0 | Bilateral palm treatment completed in 15-20 minutes. Tiny needle marks invisible within 1 hour. Resume all activities; can drive immediately. |
| Day 3-5 | First subjective dryness reported. 30-40% sweat reduction measurable on starch-iodine retest. |
| Day 7-10 | 60-70% sweat reduction. Patients report ability to handle paper without smudging. |
| Day 14 | Peak 80-90% sweat reduction reached. Confirmed by retest. |
| Month 1-6 | Stable, sustained dry palms. Routine activities (handshakes, exams, formal events) untroubled. |
| Month 6-9 | Effect gradually wears off. Maintenance treatment recommended at 7-8 months. |
Palm Hyperhidrosis Botox Pricing -- RE:BERRY Gangnam
All prices include VAT. Your exact quote is confirmed at an in-person consultation.
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Palm Hyperhidrosis Results at RE:BERRY Gangnam
Representative photographic and starch-iodine test results from palmar botulinum toxin treatment at RE:BERRY Clinic Gangnam.
Palm Hyperhidrosis Treatment Options Compared
| Feature | Botox 100U (RE:BERRY) | Iontophoresis | ETS Surgery |
|---|---|---|---|
| Mechanism | Blocks acetylcholine at sweat glands | Mineral ion blockade of ducts | Permanently cuts sympathetic chain |
| Sweat Reduction | 80-90% | 30-50% | 95%+ |
| Duration | 6-9 months | Maintenance every 1-2 weeks | Permanent |
| Downtime | Zero | Zero | 2-4 weeks |
| Compensatory Sweating | No | No | Common (50-90%) |
| Reversible | Yes (wears off) | ✓ | No |
| Best For | Most patients, all severities | Mild-moderate, daily maintenance OK | Severe + failed all conservative |
Meet Your Doctor

Dr. Yoon-Gon Ryu
- CEO / Medical Director, RE:BERRY Clinic Gangnam (License 131644)
- Former Associate Director, Pangpang Clinic Sinsa Branch
- Regular Member, Korean Academy of Aesthetic Medicine
- Member, Korean Society for Stem Cell Research
- Revinas KOL / Juvelook KOL
- Featured in Authority Magazine (2026)
Medically reviewed by Dr. Yoon-Gon Ryu, CEO / Medical Director (License 131644), RE:BERRY
The Science Behind Palmar Hyperhidrosis Botox
Mechanism, dosing rationale, and evidence supporting 100-unit grid-pattern palmar botulinum toxin treatment.
Mechanism: Acetylcholine Blockade at Eccrine Glands
Eccrine sweat glands are innervated by post-ganglionic sympathetic fibers that paradoxically release acetylcholine (rather than noradrenaline) at the neuroglandular junction. Botulinum toxin type A cleaves SNAP-25, preventing vesicular acetylcholine release and silencing the sweat gland for the duration of nerve terminal reinnervation. Carruthers (2007, J. Cosmet Dermatol, PMID:18086050) reviewed dosing pharmacology supporting the modern grid-injection technique for focal hyperhidrosis.
100 Units Per Palm: Dose-Response Evidence
A randomized study published in Dermatologic Surgery comparing 50U, 100U, and 150U per palm demonstrated that 100U is the dose-response inflection point: 100U produced 80-90% gravimetric sweat reduction with median duration of 6-9 months, while 50U gave only ~50% reduction lasting 3-4 months and 150U did not significantly improve over 100U (Kim 2018, PMID:30062800). RE:BERRY Gangnam follows this 100U-per-palm protocol as the optimal benefit-to-cost balance for international patients.
Grid Pattern Spacing: 1-1.5cm Reference
The grid pattern at 1-1.5cm intervals reflects published diffusion radius of botulinum toxin in dermal tissue. At this spacing, the field-effect zones of adjacent injections overlap by 15-25%, ensuring no gap of unsilenced glands. Park et al. (2019, J. Cosmet Dermatol, PMID:31197861) published a Korean cohort confirming this spacing optimizes both efficacy and number of injection points -- larger spacing leaves untreated patches, smaller spacing increases pain without efficacy gain.
Intradermal vs. Intramuscular Depth
Palmar injection must remain intradermal (2-3mm). Deeper intramuscular spread risks transient weakness of thenar (thumb opposition) and hypothenar muscles, occasionally reported in literature as a minor and self-limiting complication. A 2021 Korean clinical analysis by Lee et al. (J. Cosmet Dermatol, PMID:34227190) identified depth control as the single most operator-dependent variable, recommending 32G needles at 2-3mm and avoiding the deeper thenar eminence muscle plane. Dr. Ryu uses this protocol throughout.
Korean Clinical Evidence
Korean cohort data confirms palmar hyperhidrosis Botox safety and efficacy in Asian palmar anatomy. Park (2019, PMID:31197861) and Lee (2021, PMID:34227190) both report HDSS improvement ≥2 grades in 85-92% of treated patients, with a touch-up rate under 10% when grid spacing is maintained at ≤1.5cm. Korean patients tend to report slightly higher pain scores than European cohorts (likely due to thinner palmar dermis), so RE:BERRY Gangnam combines EMLA + ice pre-cooling as standard protocol.
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Palm Hyperhidrosis Botox in Gangnam -- FAQ
Frequent questions from international patients about palmar botulinum toxin treatment at RE:BERRY Gangnam.
Who performs palm hyperhidrosis botox at RE:BERRY Gangnam?
At RE:BERRY Gangnam (Gangnam Station Exit 10, 2 min walk), Dr. Yoon-Gon Ryu (Lic.131644), CEO and Medical Director, personally performs every palmar botulinum toxin injection. 100 units per palm administered in a 1-1.5cm grid pattern. KHIDI M-2025-01-08-09203 international patient attraction registration.
How much does palm hyperhidrosis botox cost in Gangnam vs my home country?
Current pricing at RE:BERRY starts from ₩69,000 (about $49). The full price list is in the Pricing section above, and your exact quote is confirmed at a free consultation.
Will Dr. Ryu also handle my consultation, or is the doctor different from the injector?
At RE:BERRY Gangnam, Dr. Yoon-Gon Ryu (Lic.131644) personally conducts the HDSS severity grading, Minor's iodine-starch test, and the grid-pattern injection in a single session (Gangnam Station Exit 10, 2 min walk). Nothing is delegated to nurses. KHIDI M-2025-01-08-09203.
How many injection points does palm hyperhidrosis treatment require at RE:BERRY Gangnam?
At RE:BERRY Gangnam, Dr. Yoon-Gon Ryu (Lic.131644) uses 25-30 grid points per palm at 1-1.5cm spacing, delivering 2-3 units of botulinum toxin per point for a total of 100 units (Gangnam Station Exit 10, 2 min walk). A 32G ultra-fine needle with 30-min EMLA + ice pre-cooling keeps pain at 3-4/10 VAS.
How long does the palm hyperhidrosis effect last?
Palmar botulinum toxin effect lasts 6-9 months at RE:BERRY Gangnam -- longer than the 4-6 months reported for underarm treatment. Maintenance is typically scheduled at month 7-8 to prevent any return of bothersome sweating. Touch-up at 50% price is offered if any wet patches persist at the 4-week retest.
Are there hidden fees for palm hyperhidrosis botox at RE:BERRY Gangnam?
RE:BERRY Gangnam publishes 100% of pricing upfront: single palm, bilateral, combined palm + underarm. Only 10% VAT is added. No separate consultation, mapping, or aftercare fees. KHIDI M-2025-01-08-09203.
Will I have temporary hand weakness after palmar botox?
Dr. Ryu injects intradermally at 2-3mm depth using a 32G needle, deliberately staying above the thenar (thumb opposition) and hypothenar muscle planes. Transient grip weakness has been reported in literature at higher doses or deeper injection, but with strict 100U intradermal protocol, the rate at RE:BERRY Gangnam is below 2% and resolves within 2 weeks.
Can I get palmar and underarm hyperhidrosis treated in the same session?
Yes. The Combined Palm + Underarm Hyperhidrosis package at RE:BERRY Gangnam treats both palms (200U total) plus both underarms (100U total) in one ~40-minute session Mapping, anesthesia, and injection are coordinated to minimize total clinic time.
Is palm hyperhidrosis botox safe during pregnancy or breastfeeding?
Botulinum toxin is contraindicated during pregnancy (Pregnancy Category C) and not recommended during breastfeeding. RE:BERRY Gangnam screens for pregnancy and lactation status at consultation. Treatment can be safely deferred and rescheduled.
How is palm hyperhidrosis different from iontophoresis or ETS surgery?
Botulinum toxin gives 80-90% reduction lasting 6-9 months with zero downtime. Iontophoresis requires ongoing 1-2 weekly home sessions for only 30-50% reduction. ETS (endoscopic thoracic sympathectomy) is permanent but causes compensatory sweating elsewhere in 50-90% of patients -- Dr. Ryu does not recommend ETS as first-line treatment.
Can I drive or use my phone right after the treatment?
Yes. Bilateral palm treatment takes 15-20 minutes total, and patients can drive and use touchscreens immediately. Tiny needle marks disappear within an hour. The only restrictions: avoid intense gripping activities, hand massages, and saunas for 24 hours.
Do you use Allergan Botox, or Korean brands?
RE:BERRY Gangnam offers patient choice of botulinum toxin: Allergan Botox, Xeomin (Merz), or KFDA-approved Korean brands such as Coretox, Nabota, or Hutox. All are real, KFDA-approved Type A neurotoxins. The standard palm price uses a Korean KFDA-approved brand; Allergan Botox upgrade extra per palm.
What is HDSS and how is severity graded?
The Hyperhidrosis Disease Severity Scale (HDSS) is a 4-point patient-reported scale (1 = never noticeable, 4 = always noticeable, always interferes). HDSS ≥3 is the typical treatment indication. Dr. Ryu also performs Minor's iodine-starch test to objectively map active sweat zones.
Will my insurance cover palm hyperhidrosis treatment in Korea?
Palmar hyperhidrosis botulinum toxin is a non-covered medical service in Korea (private pay). Some international insurance plans reimburse hyperhidrosis treatment with a doctor's diagnosis letter -- RE:BERRY Gangnam can issue a multilingual treatment certificate listing HDSS score, dose, and lot numbers on request.
How do I book a palm hyperhidrosis consultation at RE:BERRY Gangnam?
WhatsApp +82-10-4201-9133 to book, or use the booking form on this page. Same-day and next-day appointments are usually available. Consultations are in English, Chinese, Japanese, Spanish, Mongolian, Thai, Arabic, or Korean. KHIDI M-2025-01-08-09203.
Book Palm Hyperhidrosis Botox at RE:BERRY Gangnam
100U per palm bilateral package grid pattern, lasts 6-9 months. Dr. Yoon-Gon Ryu (Lic.131644). Gangnam Station Exit 10, 2 min walk. KHIDI M-2025-01-08-09203.
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- ✓ No downtime treatments available
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How to Find RE:BERRY Gangnam
2 minutes from Gangnam Station Exit 10. B1–B2, KI Tower — the building with the all-black entrance you can't miss.
RE:BERRY Clinic Gangnam
B1–B2, KI Tower, 69-gil 8, Gangnam-daero, Seocho-gu, Seoul
서울시 서초구 강남대로69길 8, 지하1·2층 (KI타워)
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