Skin Botox What Dermotoxin Is, Explained
Skin botox, also called dermotoxin, is botulinum toxin diluted well below wrinkle strength and set into the upper dermis, so it reaches the oil glands and follicle muscle behind shine and open pores while your expressions keep moving, just steps from Gangnam Station in Seoul.
Skin Botox
Dermotoxin
Skin Botox ยท Dermotoxin Explained ยท Gangnam Seoul
Skin botox, also called dermotoxin, is botulinum toxin diluted well below wrinkle strength and set into the upper dermis, so it reaches the oil glands and follicle muscle behind shine and open pores while your expressions keep moving, just steps from Gangnam Station in Seoul.


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Incheon AirportWhat is skin botox, and how is it different from regular botox?
Skin botox, also called dermotoxin, is a micro-dose of botulinum toxin placed shallow in the dermis rather than deep in the muscle. Regular botox relaxes an expression muscle to soften a wrinkle; skin botox stays about half a millimeter to a millimeter down, where it meets the sebaceous glands and the tiny arrector muscles that hold pores open. The point is oil and pore appearance and a smoother surface, not frozen expression, and at RE:BERRY Gangnam every case runs under one licensed physician from the first read of your skin to the review.
Effects & Progress
Effects & Progress
Settling the small muscle at each follicle takes the tension off the pore wall, so the skin reads finer and the pores look smaller across the treated area when you compare it under the same clinic light.
Each deposit leaves a dot of pink that clears inside the hour or so. Nothing is open; foundation is fine a few hours on and whatever you had booked for the day goes ahead.
The face begins feeling less oily to the touch and the pores read a touch finer as the dose beds into the skin's oil glands and the small follicle muscle.
Peak window: shine is at its lowest and pores at their finest for most people, and makeup keeps its finish deeper into the day. How fast this lands differs from person to person.
Holding phase. The skin-layer effect tapers across roughly three to four months as the nerve endings come back; RE:BERRY will advise the repeat timing that fits your face.
Treatment Process
Skin Botox โ Understanding the Session in the Order It Happens
โป Illustrative images are AI-generated to help explain the treatment process.Effects & Progress
Effects & Progress
Treatment Process
Skin Botox โ Understanding the Session in the Order It Happens
โป Illustrative images are AI-generated to help explain the treatment process.What Skin Botox Works On, and How the Change Reads Over Time
- Pore appearance from the muscle side: quieting the tiny arrector muscles at each follicle eases the pull that holds pores open, so the surface reads tighter across the treated cheeks and nose
- Oil at the gland: the shallow dose reaches the sebaceous glands that share the same cholinergic signaling the toxin interrupts, so midday shine across the T-zone eases for skin that runs oily
- Expression stays yours: because the toxin never reaches the frown and smile muscles below, dermotoxin changes skin quality without touching how your face moves
- Even coverage by design: the 200-300 droplets are spaced across the whole zone, so the smoothing lands evenly and avoids patches
- A skin-quality change, not a filling or lifting one: nothing adds volume and nothing tightens sagging; the surface simply reads more refined as oil and pores settle
- One physician throughout: the doctor who reads your oil pattern draws the map, places every droplet, and reads your review, with the sealed MFDS-cleared product confirmed in front of you
| Timeline | What to Expect |
|---|---|
| Pinpoint redness at each droplet usually fades within the hour; there is no wound, makeup is fine a few hours later, and the rest of your Seoul day carries on | |
| Skin often starts to feel less greasy to the touch and pores read a shade tighter as the toxin settles into the dermal glands and fine follicle muscle | |
| The main window: oil control peaks and pore appearance is at its smoothest for most guests, and foundation tends to sit flatter through the day | |
| The dermal effect eases as nerve endings recover; a repeat is considered from your review, and RE:BERRY guides the interval that suits your skin |
The Evidence Behind Intradermal Botulinum Toxin for Skin
Botulinum toxin type A blocks the release of acetylcholine at the nerve ending. In classic wrinkle treatment that block quiets a muscle of expression; placed shallow in the dermis, the same block reaches structures that also run on cholinergic signaling, namely the sebaceous glands and the fine arrector muscles at each follicle. The foundational efficacy and safety of botulinum toxin type A for the face was established in a large randomized, placebo-controlled trial by Carruthers, and it is that safety record that made the intradermal, micro-dose approach worth exploring.
Carruthers JA, Lowe NJ, Menter MA, et al. A multicenter, double-blind, randomized, placebo-controlled study of the efficacy and safety of botulinum toxin type A in the treatment of glabellar lines. J Am Acad Dermatol. 2002;46(6):840-849. doi:10.1067/mjd.2002.121356
The gland-quieting mechanism is clearest in sweat: a controlled trial of botulinum toxin type A for bilateral axillary hyperhidrosis by Naumann and Lowe showed a marked, sustained drop in sweat output, direct evidence that the toxin dials down glandular secretion when it reaches the gland. Skin botox borrows that same principle for the sebaceous glands, keeping the dose in the dermis so oil output eases while the muscles of movement are untouched. Two studies of dermally placed toxin bear on the skin indication specifically: Rose and Goldberg evaluated intradermal injection of botulinum toxin for the face and reported measurable improvement in oiliness and pore appearance, and Wu described a diluted, widely distributed 'microbotox' technique across the lower face and neck that refined surface texture and sheen without freezing expression.
Naumann M, Lowe NJ. Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomised, parallel group, double blind, placebo controlled trial. BMJ. 2001;323(7313):596-599. doi:10.1136/bmj.323.7313.596
Rose AE, Goldberg DJ. Safety and efficacy of intradermal injection of botulinum toxin for the treatment of oily skin. Dermatol Surg. 2013;39(3 Pt 1):443-448. doi:10.1111/dsu.12097
What the evidence base does not claim matters as much as what it does. Dermotoxin is a skin-quality treatment; it does not fill, lift, or lighten pigment, and the studies frame it as oil and pore refinement, not a one-time fix for enlarged pores. That is why the physician at RE:BERRY Gangnam screens the concern first: oily, congested-looking skin responds to the shallow protocol, while pigment goes to a laser class and slackness to an energy device, so the tool matches what the skin actually needs.
Wu WTL. Microbotox of the lower face and neck: evolution of a personal technique and its clinical effects. Plast Reconstr Surg. 2015;136(5 Suppl):92S-100S. doi:10.1097/PRS.0000000000001827
Skin Botox vs Regular Botox vs a Pore Laser: Reading Them by Layer
| Criteria | Skin Botox / Dermotoxin (RE:BERRY Gangnam) | Regular Muscle Botox | Pore-Refining Laser |
|---|---|---|---|
| Injection or energy layer | Upper dermis, roughly 0.5-1mm deep | Expression muscle, several millimeters deeper | No injection; light energy into the skin |
| What it acts on | Sebaceous glands and follicle arrector muscle | The muscle that creases the skin into a wrinkle | Water and pigment targets in the skin |
| Main purpose | Oil control, pore appearance, surface texture | Softening dynamic wrinkles | Texture and pore refinement by resurfacing |
| Effect on expression | Expression is left moving | The treated expression is intentionally relaxed | No effect on expression |
| Points or passes | 200-300 shallow micro-droplets | A handful of deeper points per area | Multiple laser passes over the zone |
| Downtime | Pinpoint redness fades within the hour, no wound | Small dots, minimal downtime | Redness or flaking depending on the device |
| How the result reads | Smoothest around weeks two to three | Wrinkle softens over the first days to a week | Builds over a course of sessions |
| Typical repeat | Around three to four months | Around three to four months | Varies by laser and plan |
Why This Matters
The cleanest way to keep these apart is by depth. Skin botox and muscle botox are the same drug, but the millimetre of difference in where the needle stops changes everything downstream: shallow, and the toxin meets oil glands and follicle muscle for skin quality; deep, and it meets the muscle that folds a wrinkle. A pore laser sits outside that comparison entirely, working with light and no needle at all. Many RE:BERRY Gangnam guests plan skin botox for oil and a laser for texture on separate visits because the two act on different structures.
The most common worry is a frozen face, and it comes from picturing the deep injection. Because dermotoxin stays in the dermis, above the muscle, expression keeps moving in the large majority of cases; the change is confined to the skin surface. This is the practical difference the physician explains during mapping, and it is why the treatment is often chosen by people who want their oil and pores calmer but their face fully mobile.
KHIDI's 2025 international patient survey found 41.4% of respondents rank keeping the same doctor throughout as their leading criterion. At RE:BERRY the physician who reads your oil pattern maps the points, places every droplet, and reads your review, with no handoff between stages.
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How Skin Botox Is Planned and Priced at RE:BERRY Gangnam
Your Medical Director

Dr. Yoon-Gon Ryu
- Medical Director, RE:BERRY Aesthetic Clinic Gangnam โ Korean MOHW Medical License No.131644
- Manufacturer-appointed KOL invited to teach injection and energy-device technique to Korean peers
- Regular Member, Korean Academy of Aesthetic Medicine
- Co-manages every case with Dr. Yejin Oh (Korean MOHW Medical License No.144238)
- Featured in Authority Magazine (2026)



Medically reviewed by Dr. Yoon-Gon Ryu, CEO / Medical Director, RE:BERRY
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Skin Botox, Answered: The Reference Questions
Is skin botox the same thing as dermotoxin?
Yes. Skin botox and dermotoxin are two names for the same approach: botulinum toxin diluted well below wrinkle strength and placed shallow in the dermis, above the expression muscle. Some clinics also call it micro botox or intradermal botox. At RE:BERRY Gangnam the physician confirms during mapping that this shallow, oil-and-pore approach is what your skin actually needs.
What layer of the skin does the needle actually reach?
The droplets land in the upper dermis, roughly half a millimeter to a millimeter down. That depth is the whole point: it puts the toxin at the sebaceous glands and the tiny arrector muscles around each follicle, and keeps it well above the frown and smile muscles that a standard botox injection targets several millimeters deeper. Staying shallow is what separates a skin-quality result from a wrinkle result.
Why doesn't skin botox freeze my expressions the way regular botox can?
Because the toxin never reaches the muscles of expression. Those sit below the dermis, and dermotoxin is placed above them, in the skin itself. The dose per point is also a small fraction of a wrinkle dose. In the large majority of cases the face moves completely normally afterward, and the physician explains this during mapping so you know what to expect before the first droplet.
How does quieting a muscle make my pores look smaller?
Each follicle has a tiny arrector muscle attached to it, and that muscle's pull is part of what holds a pore open. Placed shallow, the toxin eases that pull, so the pore reads tighter and the surface looks smoother across the treated zone. It is a gradual smoothing under matched clinic lighting, not an overnight change, and it lands evenly because the 200-300 points are spread across the whole area.
How does it calm oil and shine?
Sebaceous glands run on the same cholinergic nerve signaling that botulinum toxin interrupts. Keeping the dose in the dermis lets it dial down oil output while the muscles of movement stay untouched. For skin that runs oily, midday shine across the T-zone and cheeks eases through roughly weeks two to four, and foundation tends to sit flatter through the day as the surface settles.
What concerns is skin botox actually meant for, and what is it not for?
It is a skin-quality treatment for oiliness, shine, open-looking pores, and rough surface texture. It does not fill hollows, lift sagging, or lighten pigment. If your main concern is dark spots or slackness, the physician points you toward a laser or an energy device instead. Matching the concern to the right tool is the first thing done at the consultation, before any injection.
How many injection points are involved, and does it hurt?
A session is usually 200-300 shallow droplets across the mapped zone. Because they sit so close to the surface and an anesthetic cream is applied beforehand, most guests describe it as mild stinging at each point, well short of real pain. A pinpoint of redness appears at each dot and generally fades within the hour.
When will I see the change, and how long does it hold?
Skin often feels less greasy within the first week, and oil control and pore appearance reach their smoothest around weeks two to three. The dermal effect then eases over roughly three to four months as nerve endings recover. The physician sets any repeat interval from your four-week review, not from a fixed schedule.
Is there downtime, and can I fit it into a short Seoul trip?
There is no meaningful downtime. The pinpoint redness fades within the hour and there is no wound, so makeup is fine a few hours later and flights, sightseeing, and dinner all fit the same day. Guests often have the session on the first day of a trip and carry on with the rest of their plans right after.
Can skin botox be combined with other treatments?
It pairs naturally with treatments that act on other structures, such as a hydration booster or a resurfacing session, because dermotoxin works only on oil glands and follicle muscle at a fixed shallow depth. The physician sets the order and spacing so a resurfacing pass does not disturb the freshly placed droplets, and the whole plan stays under one doctor from mapping through review.
What toxin product is used, and can I see it?
A sealed, MFDS-cleared botulinum toxin type A is used, and it is shown to you and reconstituted where you can watch before anything begins, so the product is never out of sight. The physician also confirms the diluted concentration for the mapped zones, since a skin botox point carries far fewer units than a wrinkle point.
Am I a good candidate, or should I look at something else?
Good candidates have oily or congested-looking skin, open-reading pores, and a wish to keep expression fully mobile. Skin botox is not planned during pregnancy or for certain neuromuscular conditions, which the physician screens for. If the real concern turns out to be pigment or slackness, the consultation redirects you to the treatment class that fits and does not proceed anyway.
How do I book skin botox in Gangnam as a foreign visitor?
Message RE:BERRY on WhatsApp with your travel dates and a few photos of your skin; a coordinator replies in English within 24 hours and reserves a physician slot. The clinic is reservation-only for international guests, staff interpreters cover 8 languages, and the consultation and session fit into a single visit.
Where is the clinic, and how do I get there from Gangnam Station?
RE:BERRY sits inside KI Tower on Gangnam-daero, a 2-minute walk from Gangnam Station Exit 10 on Seoul Metro Line 2. It is reachable from Incheon Airport by AREX plus subway or by direct taxi, so the appointment slots cleanly between Gangnam sightseeing, dining, and shopping.
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Every device at RE:BERRY is MFDS-certified and manufacturer-verified. We never use counterfeit or grey-market equipment.
Book Your Skin Botox Consultation in Gangnam
Send a few photos of your skin and your travel dates to RE:BERRY on WhatsApp; a coordinator replies within 24 hours to reserve a physician slot. The doctor who reads your oil pattern maps every point, places each droplet, and reads your review, and nothing is scheduled until you confirm.
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Science Intradermal botulinum toxin for oil and pore refinement, peer-reviewed references
Skin botox rests on the same drug whose facial safety and efficacy were established in randomized, placebo-controlled work: Carruthers (2002) confirmed botulinum toxin type A for the face at scale, the record that made a shallow, micro-dose use worth studying. Its gland-quieting action is most directly shown in sweat: Naumann and Lowe (2001) documented a marked, sustained drop in glandular secretion after botulinum toxin type A, the mechanism dermotoxin borrows for the sebaceous glands. Dermal placement for skin specifically was evaluated by Rose and Goldberg (2013), who reported improvement in oiliness and pore appearance from intradermal injection, and by Wu (2015), whose diluted microbotox technique across the lower face and neck refined surface texture and sheen while keeping expression mobile.
- Carruthers JA, Lowe NJ, Menter MA, et al. A multicenter, double-blind, randomized, placebo-controlled study of the efficacy and safety of botulinum toxin type A in the treatment of glabellar lines. J Am Acad Dermatol. 2002;46(6):840-849. doi:10.1067/mjd.2002.121356
- Naumann M, Lowe NJ. Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomised, parallel group, double blind, placebo controlled trial. BMJ. 2001;323(7313):596-599. doi:10.1136/bmj.323.7313.596
- Rose AE, Goldberg DJ. Safety and efficacy of intradermal injection of botulinum toxin for the treatment of oily skin. Dermatol Surg. 2013;39(3 Pt 1):443-448. doi:10.1111/dsu.12097
- Wu WTL. Microbotox of the lower face and neck: evolution of a personal technique and its clinical effects. Plast Reconstr Surg. 2015;136(5 Suppl):92S-100S. doi:10.1097/PRS.0000000000001827
These references shape how skin botox is planned at RE:BERRY's Gangnam aesthetic clinic: the physician screens the concern first so oil and pore cases receive dermotoxin while pigment and laxity are directed elsewhere; the dose is diluted and kept in the dermis so glands and follicle muscle are reached without touching expression; and the treated skin is documented under standardized lighting before the session and again at the four-week review, so oil and pore change is judged from matched photographs. This information is for educational purposes only and is not medical advice.
How to Find RE:BERRY Gangnam
2 minutes from Gangnam Station Exit 10. B1โB2, KI Tower โ the building with the all-black entrance you can't miss.
RE:BERRY Clinic Gangnam
B1โB2, KI Tower, 69-gil 8, Gangnam-daero, Seocho-gu, Seoul
์์ธ์ ์์ด๊ตฌ ๊ฐ๋จ๋๋ก69๊ธธ 8, ์งํ1ยท2์ธต (KIํ์)
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